Single-cell atlas maps immune and metabolic shifts in testicular mixed tumors
A new single-cell transcriptomic atlas of testicular mixed germ cell tumors identifies 13 major cell types, m6A machinery upregulation and ...
Tag: m6A RNA modification
Fly Study Reveals How the RNA Modifier Mettl16 Shapes Development and Fertility
New research in fruit flies shows that the RNA methyltransferase Mettl16 is dispensable for survival but essential for fertility, acting ...
Estrogen receptor fuels breast cancer growth through an RNA-tagging loop, study finds
New research reveals that estrogen receptor alpha drives an m6A-dependent RNA stabilization pathway through HNRNPC and DDX6 that promotes the ...
RNA Tagging Enzyme METTL16 Fuels Colorectal Cancer by Hijacking Amino Acid Metabolism and Silencing Immune Cells
New research shows that the RNA methyltransferase METTL16 drives colorectal cancer growth and immune evasion by stabilizing BCAT1 mRNA and ...
Hypoxia Rewires RNA Methylation to Drive Pancreatic Neuroendocrine Tumor Growth
A new study reveals how low oxygen strips m6A methylation marks from tumor cell RNA, unleashing a signaling cascade that ...
GPSM2 Drives Pancreatic Cancer via m6A-Modified YAP1 mRNA
Pancreatic cancer has long been one of medicine's most stubborn adversaries, a disease so aggressive and so difficult to detect ...
M6A Modification Influences Chromatin TADs in MLLr+ AML
In an exciting new study published in Molecular Cancer, researchers have uncovered the intricate relationship between RNA modifications and chromatin ...
N6-Methyladenosine Methylation Identified as a Promising Therapeutic Target for Acute Lung Injury
Acute Lung Injury (ALI) remains a formidable challenge in critical care medicine, marked by devastating inflammation of the lung parenchyma ...
METTL3-Modulated circCDKAL1 Controls Allergy Inflammation Pathway
In the relentless quest to decipher the molecular intricacies underlying allergic rhinitis, a team of pioneering researchers has spotlighted a ...
m6A RNA Modification Controls Microglial Phagocytosis in Alzheimer’s
In a groundbreaking new study, researchers have unveiled the intricate molecular interplay that governs microglial phagocytosis within the context of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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