The Hidden RNA Master Switch That Behaves Differently in Every Cancer
A new review reveals how the long non-coding RNA MIR99AHG acts as a multifunctional host gene and regulatory hub whose ...
Tag: Long non-coding RNA
Hidden RNA Switch Drives Deadly Scarring of the Lungs, Study Finds
Researchers have identified an RNA-based molecular circuit involving H19, miR-103a-3p and TRIOBP that drives the scar-forming transformation of lung cells ...
TFEB Drives Rare Kidney Cancer Growth Through a Long Non-Coding RNA Relay
New research reveals that the Alpha-TFEB fusion gene drives t(6;11) translocation renal cell carcinoma by activating the long non-coding RNA ...
Scientists Cut Ovarian Cancer’s Glutamine Fuel Line by Blocking a Single RNA Switch
Researchers in China have identified a long non-coding RNA, SLC39A13-AS1, that drives glutamine addiction in ovarian cancer and shown that ...
Fat-Fueled RNA Signals Predict Survival and Drug Response in Lung Cancer
A new integrative study identifies three lipid metabolism-related long non-coding RNAs that predict survival, immune landscape, and drug sensitivity in ...
Cell-by-cell maps reveal hidden complexity of genomic imprinting in maize
A new study combining spatial transcriptomics and single-nucleus RNA sequencing shows that genomic imprinting in maize endosperm is far more ...
Three Hidden RNA Molecules Revealed as New Clues in Colorectal Cancer Detection and Treatment
A new study finds three antisense long non-coding RNAs are consistently elevated in colorectal cancer tissue, with HMMR-AS1 uniquely falling ...
Tiny DNA Insert in a Super-Enhancer Fine-Tunes Two Cancer Genes in Breast Tumors
A common germline insertion within a bifunctional super-enhancer dampens the expression of the cancer-promoting genes LINC00636 and CD47 in breast ...
Hidden RNA Switch Protects Jaw Cartilage From Osteoarthritis Damage
A newly mapped OIP5-AS1/miR-223-3p/FoxO3 regulatory axis protects jaw cartilage from degeneration, and boosting FoxO3 in rats slowed temporomandibular joint osteoarthritis.
Stress Sensor Reveals How Malaria Parasites Switch to Transmission Mode
Researchers have identified the transcription factor AP2-HS and a GDV1–antisense RNA feedback loop as the mechanism by which malaria parasites ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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