Longer Fat Chains, Shorter Lives: Lipid Elongation Emerges as a Hallmark of Aging
A Nature Aging commentary highlights research identifying lipid acyl-chain elongation as a conserved, causal and potentially reversible hallmark of aging ...
Tag: lipidomics
Aging Makes Fatty Chains Longer, and Shortening Them Extends Lifespan
A cross-species study in Nature Aging shows that lipid acyl chains lengthen consistently with age across mice, worms, flies and ...
New Multi-Reflecting Mass Spectrometer Reads Blood Chemistry With Unprecedented Precision
A multi-reflecting time-of-flight mass spectrometer with record resolution and sub-ppm accuracy enabled precise metabolite identification in serum from hospitalized COVID-19 ...
mRNA and Inactivated COVID-19 Vaccines Leave Distinct Six-Month Multiomic Imprints on Immunity
A longitudinal multiomics study of 553 Hong Kong vaccine recipients shows that mRNA-based BNT162b2 produces deeper and more durable gene ...
Early Oxygen-Boosting Enzyme Therapy Shows Promise Against Tuberculous Granulomas in Mice
A new study in BMC Infectious Diseases shows that early local catalase therapy relieves hypoxia, restores vascular health, and corrects ...
Blood Clues: How Platelet Chemistry Could Transform Ovarian Cancer Detection
A new review argues that platelet-derived lipid messengers such as thromboxane B2 could complement CA125 and HE4 as biomarkers for ...
Chemical Fingerprint in Ovarian Fluid Reveals Hidden Metabolic Chaos of PCOS
An integrated metabolomic and lipidomic analysis of follicular fluid from PCOS patients reveals widespread phospholipid depletion, triglyceride accumulation, amino acid ...
Sphingosine Rheostat Reemerges as an Immune Suppression Switch in Metastatic Colorectal Cancer
A large multi-omics study repositions the classic sphingosine-1-phosphate/ceramide rheostat from tumor cells to the stromal-immune compartment, linking the lipid imbalance ...
Lipid Fingerprinting Reveals the Hidden Chemistry That Separates Organic Lettuce from Conventional
An integrated metabolomics and lipidomics study of Hong Kong lettuce shows that organic and conventional farming leave distinct chemical fingerprints, ...
Algal Bloom Toxins Inflame Livers and Scramble Fat Metabolism in Endangered Chinese Fish
A multi-omics study shows that Microcystis aeruginosa exudates and the sphingolipid phytosphingosine drive hepatic inflammation, oxidative stress and lipid metabolic ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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