Laboratory Study Converts Fluoroform into Trifluoromethyl Radicals with Light
A laboratory study by Hokkaido University researchers used light, a ketone catalyst and a base to convert fluoroform into CF₃ ...
Tag: late-stage functionalization
AI Chemists Learn Where to Break Molecules: Active Learning Steers Drug Discovery Reactions
Researchers at ETH Zurich and Roche have combined active learning with geometric and self-supervised deep learning to predict C–H borylation ...
New Ligand Lets Nickel Catalyst Forge Drug-Like Bonds with Just a Whisper of Metal
A rationally designed bipyridine ligand and a non-nucleophilic guanidine additive enable visible-light-driven nickel catalysis to couple aryl bromides with diverse ...
Nickel Catalyst Alkylates Drug-Like Rings at Mild Temperatures
Scripps Research chemists have developed a nickel-catalysed, sulfonylhydrazide-based C–H alkylation that attaches alkyl groups to arenes and heteroarenes below 50 ...
Spirocycle Turns Sulfur Into a Multicentred Catalyst Through Through-Space Orbital Engineering
Chemists in Seoul have created a spirocyclic organosulfur catalyst whose four sulfur atoms share a single high-energy orbital, enabling powerful ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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