Bigger Cargo, Better Design: Lipid Nanoparticles Rethought for Giant Gene Editors
A new Nature Biotechnology study shows that screening ionizable lipids with gene-editor-sized RNA cargo identified LC-1, a lipid nanoparticle formulation ...
Tag: in vivo genome editing
Densely Modified RNA Guides Push Prime Editing to Nearly 70% Efficiency in Living Mice
Scientists have engineered densely chemically modified guide RNAs that boost prime editing efficiency in the mouse liver to nearly 70 ...
Efficient In Vivo Cytosine Base Editing via Virus-Like Particles and Uracil DNA Glycosylase Inhibition
Virus-like particles (VLPs) have long been heralded as a promising vehicle for delivering genome editors with high precision. However, their ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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