Natural Killer Cell Education Leaves Lasting Imprints on the Persistent HIV Reservoir
New research in Nature Immunology shows that KIR2DL1-educated natural killer cells leave durable imprints that shape which HIV-1 reservoir cells ...
Tag: Immunotherapy
Antibody-Drug Combination Falls Short in First-Line PD-L1-High Metastatic Lung Cancer Trial
The Phase 3 EVOKE-03/KEYNOTE-D46 trial found that sacituzumab govitecan plus pembrolizumab did not significantly improve progression-free or overall survival compared ...
Blood Test and Tumor Genetics Sharpen Predictions of Rectal Cancer Immunotherapy Success
New TORCH trial data show that combining SMAD4 mutation status, tumor mutational burden, and serial ctDNA with MRI assessments substantially ...
Statisticians Flag Fragile Risk Model Behind Esophageal Cancer Survival Study
A new commentary warns that the three-factor risk model proposed for esophageal cancer patients achieving pathological complete response after neoadjuvant ...
New Dementia Score Spots Treatable Rapid Decline Before It Is Too Late
A refined eight-point bedside score, the modified STAM3mP, validated in Dutch and American cohorts, detects treatable causes of rapidly progressive ...
Scientists Reveal How Rogue Antibodies Attack the Brain Protein IgLON5
A new structural study reveals how patient autoantibodies recognize the neuronal protein IgLON5, offering a molecular explanation for a rare ...
Exercise Could Help Cancer Patients on Immunotherapy, But Nobody Is Telling Them How
A qualitative study of patients with advanced bladder and kidney cancer on immune checkpoint inhibitor therapy finds they want structured ...
Therapeutic Vaccines for Ovarian Cancer Show Promise but Remain Stuck in Early-Stage Trials
A comprehensive analysis of 136 registered clinical trials reveals that therapeutic vaccines for ovarian cancer have advanced steadily for three ...
Immune Cells Caught arming the Deadliest Breast Cancer to Spread
New research reveals that inflammatory macrophages fuel metastasis in triple-negative breast cancer by activating a stress-signaling pathway in tumor cells ...
AI-Designed Gasdermins Programmed to Destroy Virus-Infected Cells
A Cell Research article examines how artificial intelligence-guided engineering of gasdermin pore-forming proteins could be harnessed to selectively eliminate virus-infected ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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