Hidden Immune Cells Offer New Hope Against the Deadliest Lung Cancer
WEHI researchers have discovered that gamma delta T cells can recognise and kill small cell lung cancer, and that two ...
Tag: Immunotherapy
Hidden Cell-to-Cell Messaging Networks Drive Triple-Negative Breast Cancer Resistance
A new review argues that triple-negative breast cancer's heterogeneity and therapy resistance emerge from spatially organized paracrine signaling networks between ...
Genetic Switch Lets CAR-T Cells Turn Themselves On and Off Inside Tumours
Scientists at the Italian Institute of Technology in Naples have engineered CAR-T cells with a synthetic genetic switch that activates ...
A Fat-Burning Switch That Turns Immune Cells Into Cancer Killers
Cold Spring Harbor Laboratory researchers found that activating the transcription factor PPARD in immune cells, including CAR T cells, boosts ...
Enhanced CAR T-Cell Therapy Shows Promise in Trial for B-Cell Blood Cancers
A phase I trial at Ohio State found that CAR T cells engineered to target three B-cell proteins and boosted ...
Dual Immunotherapy Clues Reveal How to Wake the Immune System Against Glioblastoma
Two UCLA-led studies identify T-cell infiltration as the key to effective glioblastoma immunotherapy and introduce a preclinical model that recreates ...
Immune Molecule B7-H3 Drives Triple-Negative Breast Cancer Through a Hidden Protein Machinery
New research reveals that the immune checkpoint protein B7-H3 fuels triple-negative breast cancer from within by sustaining SP1-dependent HSPA8 chaperone ...
Lipid Nanoparticles Reprogram NK Cells Inside the Body to Fight Cancer and Autoimmune Disease
MIT engineers have developed lipid nanoparticles that reprogram natural killer cells inside the body to destroy cancerous and autoreactive T ...
Blocking FGFR Signaling Supercharges Immunotherapy in Hard-to-Treat Colorectal Cancer
New research shows that inhibiting the FGFR signaling pathway reduces T cell exhaustion and repolarizes macrophages, significantly enhancing PD-1 blockade ...
When Tumors Hide Their Flags, Natural Killer Cells May Take Over Against Colorectal Cancer
Two patients with microsatellite-unstable metastatic colorectal cancer and markedly reduced HLA-I expression achieved durable responses to pembrolizumab, suggesting that NK ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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