AI models fuse multi-omics data to predict immunotherapy response in cancer
A narrative review in Cancer Cell International outlines how artificial intelligence can integrate genomic, transcriptomic, imaging, and other multi-omics data ...
Tag: Immunotherapy
Editorial reviews multi-omics evidence on metastatic cancer ecosystems
An editorial reviewing 15 studies finds that single-cell, spatial, metabolic, epigenetic and imaging methods expose cellular ecosystems associated with metastatic ...
Review Finds Fungal Compounds Promising, but Skin-Cancer Trials Remain Limited
A review finds that fungal compounds can suppress tumour growth, alter immunity and limit metastasis in skin-cancer models, but manufacturing, ...
Ivonescimab Extends Overall Survival Over Pembrolizumab in PD-L1-Positive Advanced Lung Cancer
A prespecified interim analysis of the phase 3 HARMONi-2 trial shows ivonescimab achieved median overall survival of 30.8 months versus ...
OSBPL3 Shapes Colorectal Cancer Progression Through Gut Microbes and Immune Microenvironment
New research links the lipid-binding protein OSBPL3 to colorectal cancer progression, gut microbiota shifts, and immune microenvironment changes, with two ...
Child recovers after probable blinatumomab lung injury and dose-escalation rechallenge
A case report describes a child with B-ALL who recovered from probable blinatumomab-associated lung injury and completed a monitored, dose-escalated ...
Global tumor board maps investigational options for glioblastoma with MDM2 and EGFR amplifications
A new Oncotarget case report details how the WIN Consortium's international molecular tumor board evaluated investigational EGFR, MDM2, CDK4/6 and ...
Lymph Node Status After Chemoimmunotherapy Predicts Survival in Esophageal Cancer
A retrospective cohort study of 194 patients with esophageal squamous cell carcinoma found that postoperative pathological lymph node stage, rather ...
Blood lncRNA RIME test refines who benefits from first-line ESCC immunochemotherapy
An exploratory multicenter biomarker analysis shows that pretreatment plasma lncRNA RIME, especially when combined with PD-L1, distinguishes patients with advanced ...
Durvalumab and olaparib combination extends survival in advanced endometrial cancer
Updated Phase 3 DUO-E trial results presented at ESMO 2026 show that durvalumab plus olaparib after chemotherapy achieved a median ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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