Tag: immune checkpoint inhibitors

A retrospective review of 35 published cases shows that nivolumab can trigger cytokine release syndrome weeks to months into treatment, ...

A phase II trial of radiotherapy followed by atezolizumab in relapsed small cell lung cancer found that radiation-induced changes in ...

A pharmacovigilance analysis of US and Japanese adverse event databases finds that PD-1 and PD-L1 checkpoint inhibitors show a robust, ...

A study of 450 colorectal cancer patients shows that POLE and POLD1 proofreading gene mutations predict markedly better immunotherapy response ...

A critical review concludes that preclinical evidence of opioid immunosuppression does not justify withholding pain relief from cancer patients, including ...

A high tumor mutational burden detected by liquid biopsy guided nivolumab treatment that produced a durable complete remission in a ...

New research reveals that radiotherapy induces PD-1 expression on tumor-associated monocytes through an adenosine-driven signaling pathway, creating an immunosuppressive cell ...

A new multi-disciplinary expert consensus provides a detailed framework for diagnosing and treating the skin toxicities caused by immune checkpoint ...

New research shows that radiation can make liver cancer cells more visible to natural killer cells, boosting the effectiveness of ...

A new review details how tumor-infiltrating lymphocyte, CAR-T, and TCR-engineered cell therapies are transforming melanoma treatment and the engineering breakthroughs ...