NUAK1 and NUAK2 drive colorectal cancer metabolic changes in cells
Human tissue associations and cell experiments link NUAK1 and NUAK2 to colorectal cancer growth, migration and metabolic reprogramming through AMPK ...
Tag: Glutamine Metabolism
Lung cancer rewires its metabolism into a dynamic, adaptive network
A new review argues that lung tumours run an integrated, adaptable metabolic network rather than isolated pathways, explaining growth under ...
Immune Cells Feed Breast Cancer Tumors as AI and DNA Testing Reshape Cancer Care
New MSK studies reveal that immune cells secretly feed triple-negative breast cancer, a CXCR2 blocker sensitizes leptomeningeal metastases to radiation, ...
How a Single Amino Acid Pathway May Steer Autoimmune Disease
A new review in the Journal of Translational Medicine details how the glutamine-glutamate metabolic axis regulates immune cell fate and ...
Blood Metabolites Emerge as Powerful New Signals for Predicting Cancer Outcomes
A new review maps how advances in plasma metabolomics detection technology are turning tumor-driven metabolic fingerprints in blood into tools ...
Scientists Cut Ovarian Cancer’s Glutamine Fuel Line by Blocking a Single RNA Switch
Researchers in China have identified a long non-coding RNA, SLC39A13-AS1, that drives glutamine addiction in ovarian cancer and shown that ...
Cancer Cells Rewire Their Fuel Supply When This Growth Signal Switches On
New research reveals that HGF/c-MET signaling reprograms glutamine metabolism in MET-amplified head and neck cancer cells through ERK-dependent induction of ...
Hidden Mitochondrial Transporters May Expose New Vulnerabilities in Colorectal Cancer
A new review highlights how three mitochondrial metabolite transporters are deregulated in colorectal cancer and jointly shape tumor metabolism, epigenetic ...
Glutamine Joins Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Cancer Trial
The phase 1 GlutaPanc trial shows that l-glutamine can be safely combined with first-line gemcitabine and nab-paclitaxel in advanced pancreatic ...
Revealing the Role of Birth in Sustaining Quiescent Neural Stem Cells
The process of birth is one of the most crucial transitions in an organism's life. The shift from the sterile ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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