SIRT1 Silences Jumping Genes by Stabilizing Heterochromatin Complexes
Researchers report that SIRT1 suppresses L1 retrotransposon activity by recruiting and stabilizing the heterochromatin factors Lamin B1 and KAP1, an ...
Tag: genomic instability
Environmental Stress May Have Loosened DNA Repair Rules on the Y Chromosome
A new hypothesis proposes that prolonged environmental stress in the ancient southern Levant transiently relaxed DNA repair constraints in one ...
Proteomic Analysis Identifies Prognostic Subgroups in SMARCA-Deficient Esophageal Cancer
A groundbreaking study has unveiled a novel proteomic landscape underlying SMARCA-deficient esophageal adenocarcinoma (EAC), shedding light on new mechanisms of ...
Complex Genetic Variation in Nearly Complete Genomes
In a groundbreaking advance, researchers have leveraged the power of long-read genome assemblies to dissect the most complex forms of ...
Rare Genetic Disorder Raises Cancer Risk by Blocking Repair of Chemo-Damaged DNA
A groundbreaking discovery has unveiled a previously unknown hereditary syndrome that critically impairs the body's DNA repair mechanisms, thus elevating ...
HKU Research Unveils PICH Protein’s Crucial Role in Safeguarding Chromosomes Against Cancer-Related Breakage
Researchers at The University of Hong Kong (HKU) have made a groundbreaking discovery regarding the intricate mechanisms that protect human ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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