Pig genetics study finds parent-of-origin effects beyond imprinting
A study in an F2 Eurasian pig population found widespread parent-of-origin effects on growth traits, including effects outside canonical imprinted ...
Tag: genomic imprinting
Genomic Imprinting’s Hidden Role in Cancer: New Methods Tackle Loss of Imprinting
A new review highlights how loss of imprinting drives tumour growth and why emerging single-cell, spatial, and long-read methods may ...
When Two Rare Diagnoses Collide: Hidden Genes Unmasked in Prader-Willi Syndrome
Chinese clinicians report the first case series of three boys with maternal uniparental disomy-type Prader-Willi syndrome who also silently carry ...
Genetic Map of Childhood Obesity Reveals Variants That Act Only in Early Life
A landmark genome-wide study of nearly 600,000 individuals identifies 624 genetic signals for childhood adiposity, many of which act only ...
New DNA Methylation Array Opens a Window onto the Human Imprintome
Researchers have developed and validated the first custom Infinium DNA methylation array dedicated to the human imprintome, covering 1,088 imprint ...
Cell-by-cell maps reveal hidden complexity of genomic imprinting in maize
A new study combining spatial transcriptomics and single-nucleus RNA sequencing shows that genomic imprinting in maize endosperm is far more ...
Placenta Gene PHLDA2 Hits Female Fetuses Harder, Mouse Study Finds
A mouse study shows that loss of imprinting of the maternally expressed gene Phlda2 depletes hormone-producing placental cells and restricts ...
Divergent epigenetic profile underlie pubertal disorders in MKRN3-associated central precocious puberty and Prader–Willi syndrome: insights from a frameshift variant
Researchers at Children's Hospital of Fudan University in Shanghai have identified the first frameshift mutation within a critical hotspot region ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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