Blood Cell Mixtures Drive Epigenetic Age Clocks, Study Reveals
A large new study shows that blood cell composition, especially the balance of naive and memory T cells and neutrophil ...
Tag: Genome Medicine
Blood Clues Before Surgery Predict Who Will Reject a New Liver
Single-cell sequencing of blood samples taken before and after liver transplantation reveals immune signatures that predict which patients will suffer ...
Deep learning reads the genome to flag ALS risk in over 47,000 people
An internationally validated deep learning model trained on genomes from more than 47,000 people can distinguish ALS patients from controls ...
Immune Fingerprints in Blood Reveal Parkinson’s Disease When Patients Are Sorted First
By stratifying Parkinson's patients into mouse-model-anchored immune subtypes, researchers have built T-cell receptor blood tests that exceed 0.8 AUC, overturning ...
Near-Perfect Long Reads Reveal Hidden Mosaicism Left Behind by CRISPR Gene Editing
Ultra-accurate targeted long-read sequencing of genome-edited zebrafish reveals widespread CRISPR-Cas9 mosaicism, with structural variants and off-target mutations inherited into the ...
Vitamin-Derived Molecule Shows First Signs of Treating Mitochondrial DNA Disease in Humans
A four-week trial of nicotinamide riboside in eight patients with mitochondrial DNA disease shows the first human evidence of molecular ...
New Statistical Model Maps How Air Pollution Reshapes the Human Microbiome
A new Bayesian spatial mixed model called SpaMixed detects air pollution effects on the microbiome by accounting for geographic and ...
New AI tool maps single cells onto tissue space with unprecedented precision
A new deep learning framework called SCmapST uses a seeded matches strategy to map single-cell gene expression data onto spatial ...
Cancer Cells Defy Quiescence Doctrine as MYC Drives a Proliferative Chemoresistance Program
A sweeping integrated genomics study reveals that chemotherapy-resistant tumors across multiple cancer types share a hyperproliferative, MYC-driven state, identifying the ...
Gut Microbes May Predict Who Keeps Weight Off After Fasting, Study Finds
A machine learning model combining baseline gut microbiome profiles with clinical variables can predict who sustains weight loss twelve weeks ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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