Hidden Sugar Signals on Pig Organs May Decide Xenotransplant Success
A new review argues that sugar-based signaling through Siglec receptors and complement Factor H forms a hidden regulatory layer determining ...
Tag: gene editing
Plant immune switches offer new blueprint for engineered disease resistance
A sweeping review maps the transcriptional, post-transcriptional, translational and post-translational switches that could let scientists program broad-spectrum disease resistance into ...
Two-Layer Gene Editing Delivers Elite Herbicide-Tolerant Crops
Researchers combined structure-guided protein design with cis-regulatory editing at the native HPPD locus to create elite herbicide-tolerance alleles in rice ...
Proteomics and First CRISPR-Cas9 Editing Point to New Liver Fluke Vaccine Targets
A comparative proteomics pipeline and the first CRISPR-Cas9 gene editing in Fasciola hepatica juveniles have identified three surface-exposed proteins as ...
Scientists Switch On an Embryonic Gene to Rescue a Lethal Blood Disorder
Oxford researchers have identified the DNA switches that silence the embryonic ζ-globin gene and shown that base editing them restores ...
Tumor Organoids Get a Four-Layer Upgrade in the Push for Precision Cancer Care
A new review in the Journal of Translational Medicine proposes a four-layer functional integration framework that combines gene editing, immune ...
CRISPR Knockout of a Single Gene Supercharges Soybean’s Health-Boosting Isoflavones
Researchers used CRISPR/Cas9 to knock out the GmMYB100 repressor gene in soybean, boosting seed daidzein levels nearly threefold and genistein ...
How Scientists Are Cracking Wheat’s Toughest Disease With Two Powerful Resistance Genes
A new review details the five types of wheat resistance to Fusarium head blight, the cloned genes Fhb1 and Fhb7, ...
Bigger Cargo, Better Design: Lipid Nanoparticles Rethought for Giant Gene Editors
A new Nature Biotechnology study shows that screening ionizable lipids with gene-editor-sized RNA cargo identified LC-1, a lipid nanoparticle formulation ...
Rewiring the Engine: How Metabolism Could Unlock CAR-T Cells for Solid Tumors
A new review argues that engineering the metabolism of CAR-T cells, alongside neutralizing the hostile chemistry of tumors, is the ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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