CagL Protein Polymorphism Fine-Tunes Helicobacter pylori Cancer Signaling
Analysis of 2,267 Helicobacter pylori genomes and gerbil infection experiments shows that a two-amino-acid polymorphism in the CagL pilus protein ...
Tag: gastric cancer
Circular RNA Hsa_circ_0000285 Emerges as a Cancer Growth Driver and Therapy Target
A new review finds that the circular RNA circ_0000285 is overexpressed in most studied cancers, where it promotes growth and ...
CD276 Blockade Slows Gastric Cancer and Boosts Anti-PD-1 Immunotherapy in Preclinical Study
Blocking the CD276 molecule slowed gastric cancer growth and, combined with anti-PD-1 therapy, produced the strongest tumor suppression and increased ...
Fc-Free CLDN18.2 × CD3 Antibody AHT-102 Shrinks Gastric Tumors in Mice
A new Fc-free CLDN18.2 × CD3 bispecific antibody called AHT-102 showed dose-dependent tumor suppression, tumor-selective tissue distribution, and no systemic ...
Computational Design Yields Four Hydrazone Candidates Against Gastric Cancer Cells
An entirely computational study designed four hydrazide–hydrazone candidates with predicted activity against the MGC803 gastric cancer cell line and prioritized ...
AI Framework Aims to Transform Helicobacter pylori Care from Diagnosis to Vaccines
A new review proposes a five-module artificial intelligence framework linking endoscopic diagnosis, genomic resistance prediction, vaccine design and digital adherence ...
Two IL-17RA Variants Show No Link to Gastric Cancer in Brazil
A Brazilian study of 301 gastric biopsy samples found no association between the IL-17RA variants rs887796 and rs1468488 and gastritis ...
Gastric Cancer Nanomedicine Promises More Than It Has Delivered, Review Finds
A critical review of 186 studies finds gastric cancer nanomedicine has delivered tolerability gains but little evidence of genuine targeted ...
CISD2 knockdown suppresses gastric cancer and triggers ferroptosis
Knocking down CISD2 suppresses gastric cancer cell growth and induces ferroptosis through inhibition of the mTOR/SREBF1/SCD1 axis and GPX4 downregulation, ...
Fibroblasts That Show Tumors’ IDs May Be Shapeshifters, Not Fixed Subtypes
A new perspective argues that antigen-presenting fibroblasts in gastrointestinal tumors are reversible states whose immune role depends on unmeasured co-stimulatory ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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