Body Clock Gene BMAL1 Plummets in Childhood Leukemia, Study Finds
A new study reports that the circadian clock gene BMAL1 and the cell cycle checkpoint regulator WEE1 are significantly downregulated ...
Tag: G2/M checkpoint
Securin Gene PTTG1 Emerges as Engine of Gastric Cancer’s Stepwise March
Single-cell sequencing, organoids, and xenografts reveal that the securin-encoding gene PTTG1 reprograms the G2/M checkpoint to drive the stepwise progression ...
ATR Inhibitor Ceralasertib Restores Trifluridine’s Power Against Drug-Resistant Colorectal Cancer
New preclinical research shows that the ATR inhibitor ceralasertib (AZD6738) synergistically restores and amplifies the antitumor activity of trifluridine in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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