PKR inhibitor imoxin fails to ease diaphragm disease in male mdx mice
Long-term treatment with the PKR inhibitor imoxin failed to reduce PKR activation, improve muscle function, or suppress inflammatory and ER ...
Tag: fibrosis
Ancient Chinese Herb Compound Halofuginone Could Be Detoxified Into Safer Cancer Drug
A new review argues that reformulating the versatile natural-product drug halofuginone as a hydrochloride salt could tame its toxicity and ...
Liver’s Master MicroRNA: How miR-122 Shapes Fatty Liver Disease, Hepatitis and Cancer
A comprehensive review shows that microRNA-122 acts as both a master regulator of liver biology and a sensitive, context-dependent biomarker ...
How the Bladder Senses Force: Biomechanics of Injury and Repair
A sweeping new review in Nature Reviews Urology reveals how mechanical forces such as stretch, pressure and shear stress actively ...
How Aging Breaks the Timing of Skeletal Muscle Repair
A new review argues that aged skeletal muscle fails to regenerate not because any single cell type collapses but because ...
Cancer’s Family Tree Gets a Map: Lineage Tracing Reveals How Tumors Grow and Spread
A new Nature Genetics study combines spatial transcriptomics and lineage tracing to map how lung tumor subclones expand, reshape their ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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