Tag: fibroblast activation protein

A narrative review indicates that FAPI PET is not yet a validated biomarker for assessing treatment response in radioiodine-refractory differentiated ...

In a prospective head-to-head clinical study, the positron emission tomography radiotracer AlF-FAPI-74 identified substantially more primary and metastatic lesions than ...

A new study establishes a robust manufacturing process for Ga-DOTA-4AH29, enabling both automated and manual clinical production of a PET ...

A clinical case series demonstrates that Gallium-68 FAPI-46 PET/CT overcomes conventional FDG imaging limitations by providing sharp lesion contrast and ...

A preclinical study evaluated the pharmacokinetics and dosimetry of Lu-FAPI targeting fibroblast activation protein in triple-negative breast cancer models.

A prospective study reveals that Gallium-68 FAPI PET/CT detects active hepatic fibroblast activation in chronic liver disease beyond traditional blood-based ...

Researchers identified an optimized human VH domain-based CAR-T cell therapy targeting fibroblast activation protein that exhibited enhanced antitumor efficacy, persistence, ...

In preclinical mouse models of neuroendocrine tumors, a dual-targeting SSTR2 and FAP heterodimer achieved tumor exposure comparable to a homodimer ...

Researchers found that fibroblast activation protein promotes vascular smooth muscle cell migration and neointimal hyperplasia, driving restenosis after surgery for ...

A comprehensive narrative review establishes that molecular PET/CT imaging for pancreatic masses must be guided by suspected tumor biology and ...