DNA Damage Tolerance Factor Rad5 Enriched at Yeast Telomeres During Replication
A mini-review in Current Genetics reports that the DNA damage tolerance factor Rad5 binds to yeast telomeres and becomes enriched ...
Tag: factor
Targeting RBM39 Disrupts Mitosis and Sensitizes Triple-Negative Breast Cancer Cells
In triple-negative breast cancer cell lines and organoids, pharmacologic targeting of the splicing factor RBM39 disrupts mitotic fidelity and increases ...
Promoter Variant Alters Nuclear Transport Protein to Modify Ataxia Symptom Onset
A genetic variant in the KPNA3 promoter alters transcription factor binding and accelerates the clinical onset of spinocerebellar ataxia type ...
Researchers Derive Streamlined Quality of Life Scale for Mexican Diabetes Patients
A psychometric evaluation in Mexico City identified a unidimensional 23-item version of the Diabetes-39 questionnaire that reliably assesses health-related quality ...
Release-factor degradation boosts readthrough of MECP2 nonsense mutations
In HeLa cells, eRF3a degradation amplified aminoglycoside-induced readthrough at MECP2 nonsense mutations but did not trigger readthrough on its own.
Geology dominates modeled risk in tunnel expansion under traffic
A single-project case study using an analytic network process found that geology dominated modeled risk on the traffic-retaining side of ...
Transformer Improves Critical Heat-Flux Prediction Under Non-Uniform Reactor Heating
A causal transformer reduced critical heat-flux prediction scatter in a held-out benchmark of 109 non-uniform-heating reactor experiments while retaining classical ...
Chengdu and Chongqing emissions shaped by growth, energy use and efficiency
A 2014–2023 decomposition study finds that economic growth and rising energy use drove carbon emissions in Chengdu and Chongqing, while ...
CFH risk variant linked to complement changes in non-AMD eyes
A study links the high-risk CFH Y402H genotype to granzyme B activity, reduced vitronectin and membrane attack complex deposition in ...
Wild Bees Drive Lavender Oil Quality and Yield
Lavender essential oil is a cornerstone of the global pharmaceutical, perfumery, and food industries, prized for its distinct aromatic profile ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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