Residual Tumor Burden After Immunotherapy Predicts Survival in Esophageal Cancer
A real-world study of 178 esophageal cancer patients shows that residual tumor grade and post-treatment lymph node status, especially ypN3, ...
Tag: esophageal squamous cell carcinoma
R-Loop Gene Signature Predicts Survival and Immune Landscape in Esophageal Cancer
Researchers have built the first R-loop-related gene signature for esophageal squamous cell carcinoma, identifying BRIX1, CHEK1, and NUP155 as core ...
Blood Test Reads DNA Methylation Patterns to Help Detect Deadly Esophageal Cancer
A large two-cohort study shows that a blood-based DNA methylation panel targeting the HYAL2, S100P and DYRK4 genes, combined with ...
Scientists Uncover a Fat-Metabolism Switch That Fuels Esophageal Cancer and Blunts Chemotherapy
A new study shows that the transcription factor ELF4 activates the enzyme UGT8, reshaping sphingolipid metabolism to drive esophageal squamous ...
PET Scan Glucose Uptake Offers Clues to Immunotherapy Biomarker in Esophageal Cancer
A retrospective study of 89 patients finds that 18F-FDG PET/CT metabolic parameters, particularly SUVmax, are statistically associated with PD-L1 expression ...
Machine Learning Pinpoints Two Genes Behind Radiotherapy Resistance in Esophageal Cancer
By integrating single-cell and bulk RNA sequencing with machine learning and laboratory validation, researchers have identified MAP1LC3B and HSD17B10 as ...
Immunotherapy After Surgery Shows Durable Results in High-Risk Esophageal Cancer
A phase II trial found that adjuvant sintilimab monotherapy after surgery met its primary efficacy endpoint with 87.5 percent one-year ...
Immune-Boosted Chemo Cuts Death Risk by a Third in Advanced Esophageal Cancer, Landmark Analysis Finds
A revised meta-analysis of six phase III trials shows first-line PD-1 inhibitor plus chemotherapy reduces the risk of death by ...
Immunotherapy Plus Chemoradiotherapy Triples Survival in Esophageal Cancer Study
A propensity score matched study from Taiwan finds that adding the immunotherapy drug nivolumab to definitive chemoradiotherapy tripled median overall ...
CYP2S1 enzyme linked to immunotherapy resistance in esophageal cancer
New research identifies the enzyme CYP2S1 as a driver of immunosuppressive cell recruitment and poor chemoimmunotherapy response in esophageal squamous ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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