CLDN4 Expression Causally Increases Ovarian Cancer Risk in Multi-Omics Study
A multi-omics study identified CLDN4 expression as causally linked to ovarian cancer risk and highlighted it as a promising therapeutic ...
Tag: eQTL
Study Identifies Thrombomodulin and Factor V as Optimal Deep Vein Thrombosis Biomarkers
Researchers prioritized thrombomodulin and factor V as the most promising blood-based biomarker candidates for deep vein thrombosis by integrating genome-wide ...
ARL6IP4 Linked to Osteoarthritis in Activated T Cells
A study in Arthritis Research & Therapy links ARL6IP4 expression in activated T cells to osteoarthritis risk, highlighting the importance ...
Tandem Repeat DNA Variation Drives Cell Type-Specific Gene Regulation in Immune Cells
A large-scale multiomic study reveals that tandem repeat variation drives cell type-specific gene expression across human immune cells.
Gene GLS May Drive Irritable Bowel Syndrome Risk Through Mannose Metabolism
A combined Mendelian randomization, SMR and mediation analysis links genetically predicted GLS expression to higher irritable bowel syndrome risk, partly ...
Massive Single-Cell Map Reveals How Rare and Common Gene Variants Steer Immunity
Phase 1 of the TenK10K consortium maps common and rare genetic variants affecting gene expression across 28 immune cell types ...
Computational Predictions Fail to Match Measured Activity at Prostate Cancer Risk Variants
A re-analysis of prostate cancer reporter assay data shows computational annotations poorly predict measured regulatory activity, while ovarian risk variant ...
Genomic scan points to seven kidney genes, but only one earns diabetes-specific support
An exploratory genomic framework combining Mendelian randomization, kidney-compartment eQTL data, and colocalization identifies seven candidate genes for kidney traits, with ...
New Whitening Method Speeds Up Giant Genetic Data Analysis
Researchers have rebuilt the whitening transformation on a probabilistic footing, making correlation removal in ultra-high-dimensional genetic data faster and more ...
Blood Gene Study Nominally Flags SLC51A and TPMT as Aneurysm Markers
An integrative analysis of blood transcriptomics and genetic data nominally prioritizes SLC51A and TPMT as exploratory candidate diagnostic genes for ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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