How the Microbiome Shapes HPV Infection and Gynecological Cancer Risk
A new review synthesizes evidence that gut and vaginal microbiota dysbiosis promotes persistent HPV infection and the development of cervical, ...
Tag: endometrial cancer
β-Catenin Inhibitors Show Potent Activity Against Double-Mutant Endometrial Cancer in Preclinical Study
A new preclinical study shows that the β-catenin/CBP inhibitor ICG-001 selectively kills endometrial cancer cells carrying both PIK3CA and CTNNB1 ...
Radiotherapy Still Matters in dMMR Endometrial Cancer, Researchers Warn in the Immunotherapy Era
A new Viewpoint in eClinicalMedicine argues that immune checkpoint inhibitors have not yet proven they can replace pelvic radiotherapy in ...
RNA Chemical Tag Drives Endometrial Cancer Through a DNA Repair Protein, Study Finds
New research reveals that the RNA modification reader ALYREF drives endometrial cancer progression by stabilizing XRCC6 mRNA and activating Wnt/β-catenin ...
Metabolic Enzyme ME1 Emerges as Key to Unlocking Progestin Therapy in Endometrial Cancer
Japanese researchers found that the metabolic enzyme ME1 predicts poor outcomes in endometrioid endometrial carcinoma and that inhibiting it restores ...
Gut Hormones GLP-1 and GIP Emerge as Unexpected Players in Women’s Health
A new review maps how the gut hormones behind blockbuster weight-loss drugs may also influence PCOS, endometriosis and gynaecological cancers.
Oral Wnt-blocking pill plus lenvatinib shows promise in endometrial cancer after immunotherapy fails
A phase 1b/2 trial found that the oral CBP–β-catenin inhibitor E7386 combined with lenvatinib produced durable responses in advanced endometrial ...
Fgl-1 Emerges as an Oncogenic Driver Fueling Endometrial Cancer Through PI3K/AKT Signaling
New research shows that fibrinogen-like protein 1 is overexpressed in endometrial adenocarcinoma and drives tumor growth, migration and invasion by ...
Women’s Cancers: The Prevention Power We Already Have but Rarely Use
A new editorial in Cancer Causes & Control argues that the most powerful tools against breast, ovarian, cervical, and endometrial ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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