Eye Damage in Diabetes May Signal Hidden Kidney and Leg Artery Disease
A large Chinese cross-sectional study of 3,000 patients with type 2 diabetes finds that diabetic retinopathy is strongly associated with ...
Tag: EGFR
Rising RNA Signal in Blood May Track Diabetic Kidney Damage in Egyptian Patients
A new study of Egyptian patients with type 2 diabetes finds that serum levels of the long noncoding RNA PVT1 ...
ADAM17 Enzyme Drives Migration in Canine Mammary Tumor Cells, Study Finds
A new study in BMC Cancer shows that the protease ADAM17 is upregulated in aggressive canine mammary carcinomas and promotes ...
Lactate Tag on Histones Fuels Drug Resistance in Head and Neck Cancer
New research shows that CBP-driven histone H3K18 lactylation activates GLI2 transcription, promoting head and neck squamous cell carcinoma progression and ...
Self-Assembling Peptide Turns Tumor Cells Into Antibody Magnets for Cancer Immunotherapy
A receptor-triggered peptide self-assembly strategy converts monomeric hapten conjugates into multivalent antibody-recruiting fibrils on EGFR-positive tumor cells, driving potent complement-mediated ...
Diabetes Drugs Unexpectedly Raise Levels of Gut Microbe-Linked Heart Risk Marker TMAO
A pooled analysis of two placebo-controlled crossover trials shows that the SGLT-2 inhibitors empagliflozin and dapagliflozin modestly but significantly raise ...
How a Single Gene Loss Helps Melanoma Outsmart Targeted Drugs
An integrative multi-omics study reveals how loss of the chromatin factor ARID1A rewires receptor and kinase signaling in melanoma, driving ...
Citrus Flavonoid Meets Nuclear Medicine in Twin Radiometal Design for Breast Cancer
Computational simulations show that the citrus flavonoid hesperidin can be paired with technetium for imaging and rhenium for therapy, with ...
Common Cosmetic Preservative Methylparaben Linked to Breast Cancer Mechanisms in Landmark Computational Study
A new computational study links the common cosmetic preservative methylparaben to five key breast cancer signaling proteins and unveils a ...
Silent Receptor Boost: Non-Signaling CARs Supercharge T-Cells Against Head and Neck Cancer
Researchers in Düsseldorf report that co-expressing a non-signaling EGFR-binding CAR alongside EGFRvIII-specific CAR T-cells enhances killing of head and neck ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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