Oral IDH1 Inhibitor Ivosidenib Holds Rare Liver Cancer at Bay for 35 Months in Case Report
A case report documents 35 months of oral ivosidenib therapy with partial remission and no adverse events in a man ...
Tag: drug
Phase 3 Trial: New Drug Cuts Endometrial Cancer Death Risk
A phase 3 trial shows sacituzumab tirumotecan significantly lowers the risk of cancer progression and death in women with recurrent ...
Selective antifungal outperformed amphotericin B in mice without kidney injury
Mandimycin M16 neutralized 11 priority fungal pathogens in vitro and outperformed amphotericin B in mouse models of systemic Candida infection ...
Severe obesity complicates ICU drug dosing, review concludes
A narrative review concludes that severe obesity can complicate ICU drug dosing and supports individualized regimens based on pharmacokinetic variability ...
Repurposed darifenacin and betamethasone potentiate streptomycin against resistant Staphylococcus aureus in vitro
An in vitro study found that a repurposed darifenacin-betamethasone formulation reduced the fitted streptomycin IC50 by 2.2-fold in a resistant ...
Antibody–drug conjugates and tumor immunity in breast cancer
A focused review finds that antibody–drug conjugates directly kill breast-cancer cells, while evidence that they remodel human tumor immunity remains ...
Ustekinumab trough levels associated with remission in 76 adults in single-center Crohn’s study
A cross-sectional study of 76 adults with Crohn’s disease at a Baghdad hospital found that higher ustekinumab trough concentrations were ...
Ivermectin blunts cisplatin effects in oral cancer cells
A laboratory study found that ivermectin weakened cisplatin-associated cytotoxicity, apoptosis and S-phase arrest in HN9 oral cancer cells.
From Farm to Fork: AI, Biosensors and Green Chemistry Join Forces to Hunt Veterinary Drug Residues in Food
A sweeping review in Food Chemistry: X maps how AI, IoT, blockchain and green analytical chemistry could transform veterinary drug ...
Most Cancer Drug Side Effects May Not Be Preventable, Vietnamese Database Reveals
A year of pharmacovigilance reports from Ho Chi Minh City shows that of 253 confirmed adverse reactions to anticancer drugs, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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