Drug Safety Evidence Has a Shelf Life: Most Harm Findings Expire Within Three Years
A large retrospective cohort study of 505 meta-analyses finds that most early evidence on medication harms expires within about three ...
Tag: drug safety
Statistician Wins FDA Funding to Quantify Record Linkage Uncertainty in Real-World Evidence
A George Mason statistician has received FDA funding to develop regulatory-grade frameworks that quantify how record linkage errors affect the ...
Genetic Framework Flags Safety Risks for Inflammatory Bowel Disease Drug Targets
A new genetics-based framework systematically flags potential safety risks for inflammatory bowel disease drug targets before broad clinical exposure.
Antidepressants and Breast Cancer: Landmark Analysis of Nearly Two Million Women Reveals Timing Matters
A meta-analysis of twenty-three studies covering nearly 1.83 million women finds that short-term SSRI use is associated with a modest ...
Fifteen Years of Data Reveal Blind Spots in Korea’s Herbal Medicine Safety Surveillance
A 15-year analysis of 454 herbal medicine adverse event reports at a Korean integrative medical center shows that nearly a ...
Computational Framework Ranks Safer RNA-LNP Formulations Before the Lab
Researchers at the University of Catania have built a modular computational framework that ranks RNA-lipid nanoparticle formulations for safety and ...
Hair Loss Signals Emerge in FDA Database as Biologics Draw New Safety Scrutiny
An analysis of six years of FDA adverse event reports finds disproportionately high reporting odds of hair loss among patients ...
MS Drug Ocrelizumab Linked to Rare Lung Disease in New Case Series
A new case series and literature review report that ocrelizumab, a leading multiple sclerosis therapy, is associated with a rare ...
Blood Pressure Drugs Differ Between Psoriasis Patients, Large US Study Finds
A cross-sectional analysis of the NIH All of Us Research Program examines whether hypertensive patients with psoriasis are prescribed different ...
Landmark Real-World Study Will Track a Breakthrough Lung Cancer Drug Across China
A new multicenter observational study called RERUN will evaluate the real-world effectiveness and safety of trastuzumab deruxtecan in about 150 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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