Early Fostamatinib Use Shows High Response Rates in Immune Thrombocytopenia
A nationwide Spanish real-world study of 72 adults with immune thrombocytopenia found that fostamatinib, an oral spleen tyrosine kinase inhibitor, ...
Tag: drug safety
Asthma Drug Montelukast Linked to Higher Risks of ADHD and Behavioral Disorders in Children
A pooled analysis of US and Canadian birth cohorts finds that children starting montelukast for asthma face significantly higher risks ...
Prewetted Membranes Could Make Sterile Drug Filtration Far More Efficient
Penn State researchers show that prewetting sterilizing-grade membranes with polysorbate 20 can boost nanoemulsion filtration capacity more than 100-fold, improving ...
Millions of Records, One Drug: Global Databases Expose Riociguat’s Hidden Risks
A large pharmacovigilance analysis of over 30,000 adverse event reports confirms riociguat's known risks and uncovers new safety signals, including ...
Immune Checkpoint Blockers Linked to Rare Blood Platelet Disorder in Two Global Drug Safety Databases
A pharmacovigilance analysis of US and Japanese adverse event databases finds that PD-1 and PD-L1 checkpoint inhibitors show a robust, ...
Common Bile Acid Drug Passes First Safety Test in Sheep, With Caveats
The first systematic safety evaluation of the choleretic drug mefepronic acid in sheep found no clinical adverse effects and stable ...
Switching to Romiplostim Offers Little Benefit for Children After Multiple Oral TPO-RA Failures
A retrospective study of 16 Chinese children with persistent or chronic immune thrombocytopenia finds that romiplostim is safe but provides ...
Two Late-Line Drugs Offer Equal Survival in Metastatic Colorectal Cancer, Landmark Study Finds
A large prospective Japanese study found that late-line treatment sequences beginning with either regorafenib or trifluridine/tipiracil plus bevacizumab yielded comparable ...
Ovarian Cancer Drug Shows Eye and Nerve Risks in Large Real-World Study
A large real-world analysis of TriNetX health records finds that mirvetuximab soravtansine carries elevated risks of corneal toxicity and peripheral ...
Vitamin A Drug Plus Platelet Booster Rescues Cancer Patients From Dangerous Therapy-Induced Platelet Loss
A retrospective study at Peking University People's Hospital found that adding all-trans retinoic acid to thrombopoietin receptor agonists restored platelet ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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