Tag: drug repurposing

A scoping review of 140 reviews finds N-acetylcysteine studied across 17 clinical domains, but widespread low-quality and redundant evidence still ...

New research shows that the diabetes drug metformin protects lymphatic vessels from mitochondrial damage caused by the chemotherapy agent 5-fluorouracil ...

University of São Paulo researchers found that fourteen derivatives of an anticancer compound kill Plasmodium falciparum at both the blood ...

Integrating single-cell and spatial transcriptomics, researchers identified a novel invasive-frontier fibroblast state and the multicellular community it defines, which independently ...

Researchers found that rabies virus hijacks the Cav1.2-KCa1.1 ion channel axis to enter cells, and that the FDA-approved calcium channel ...

Researchers report that the approved HIV protease inhibitor ritonavir binds the HCMV immediate-early protein IE1 and promotes its ubiquitin-proteasome-mediated degradation, ...

A propensity score-matched study finds that 5-HT3 receptor antagonist anti-nausea drugs are associated with significantly improved survival in patients with ...

New research shows that pairing the decades-old antipsychotic chlorpromazine with the mitochondrial fission inhibitor mdivi-1 sharply boosts cancer cell death ...

Researchers in Taiwan mapped a 25-microRNA regulatory network driving radioresistance in head and neck cancer and used transcriptome-guided drug repurposing ...

A large target trial emulation found that cancer patients on SSRIs while receiving immune checkpoint inhibitors had significantly lower two-year ...