Where a radioactive emitter sits inside a tumour cell changes simulated dose
A computational study of one breast-cancer region shows that radionuclide identity and subcellular binding location jointly shape simulated cancer-cell nuclear ...
Tag: dosimetry
FDA, EMA and NMPA differ in how they assess radiopharmaceuticals, review finds
A review published in EJNMMI Radiopharmacy and Chemistry compares how the FDA, EMA and NMPA evaluate radiopharmaceuticals before clinical use ...
Alpha Versus Beta: Tumor Architecture Decides Where Radiation Dose Lands
Monte Carlo simulations show astatine-211 delivers about 120-fold higher single-cell nuclear dose than lutetium-177, but its effectiveness depends strongly on ...
PD-L1-Targeted Lutetium-177 Radiotherapy Shrinks Triple-Negative Breast Tumors in Mice
Radiolabeled atezolizumab with lutetium-177 significantly reduced tumor volumes and extended median survival in a mouse model of triple-negative breast cancer.
Kidney Radiation Doses Stay Low in Most Men After PSMA Therapy
A retrospective analysis of 127 patients found that only 5 percent-level few exceeded 20 Gy cumulative kidney dose after lutetium-177 ...
Precision Brachytherapy Improves Dosimetry in Salvage Treatment for Recurrent Gynecologic Cancers
A retrospective study analyzed 27 patients treated with transvaginal HDR-ISBT for centrally recurrent pelvic gynecologic malignancies, finding that 3D-PT-assisted implantation ...
Why promising cancer PET tracers fail: a new evidence-gated translation roadmap
A new Frontiers in Nuclear Medicine review proposes an evidence-gated framework that separates established PSMA and somatostatin receptor theranostics from ...
Helical tomotherapy outperforms VMAT in lattice radiotherapy planning for bulky tumors
A paired dosimetric study of 22 patients found helical tomotherapy achieved steeper peak-to-valley dose gradients and better low-dose normal tissue ...
Narrative review finds synthetic CT clinical validation remains limited
A narrative review finds that deep-learning synthetic CT can improve cone-beam CT images and dose calculations, but clinical validation remains ...
Deep Breath During Radiotherapy Shields Heart in Left-Sided Breast Cancer
A paired CT study of 17 left-sided breast cancer patients shows deep inspiration breath-hold significantly cuts radiation dose to the ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!