DNA Repair Protein RAD54L Protects Developing Egg and Sperm Precursors from Toxic Enzyme Traps
New research in mice reveals that the DNA repair factor RAD54L protects primordial germ cells by stabilizing the E3 ligase ...
Tag: DNA repair
Cell Cycle Breakdown Drives Sudden Bursts of Aneuploidy in Yeast Genomes
Experiments in hundreds of diploid yeast strains show that double losses of heterozygosity arise mainly from transient bursts of whole-chromosome ...
How Seeds Cheat Time: Redox Control, DNA Repair, and Protective Proteins Hold the Key to Longevity
A new review reveals how redox homeostasis, DNA and protein repair enzymes, and protective proteins work together to preserve seed ...
DNA Repair Protein Fails to Explain Why a Common Dog Cancer Shrugs Off Chemotherapy Drug
New laboratory research shows that canine hemangiosarcoma cell lines resist the chemotherapy drug temozolomide through a mechanism independent of the ...
Cold Temperatures Rewire Plant Recombination Through a Chromosome Brake Called SNI1
A chromosome-architecture protein called SNI1 acts as a cold-sensitive brake on class II crossovers in Arabidopsis, revealing how temperature reshapes ...
Hidden Protein Trio Helps Cancer Cells Survive Radiation, Study Finds
A newly identified TIMELESS-SIRT1-Ku70 complex promotes assembly of the Ku DNA repair heterodimer, giving cancer cells resistance to radiation and ...
DNA Repair Protein APEX1 Emerges as Key Guardian of Egg Cell Quality
New research shows that the DNA repair and redox-signaling protein APEX1 protects oocyte quality by sustaining mitophagy and suppressing iron-dependent ...
Deleting a Potassium Channel Rewires How Glioblastoma Cells Respond to FLASH-Style Radiation
Deleting the BKCa potassium channel alters oxidative stress, DNA damage signaling and repair gene expression in glioblastoma cells exposed to ...
Wine Yeast’s Secret Global Highways Revealed by Population Genomics
A large-scale genomic study of the wine yeast Hanseniaspora uvarum reveals widespread intercontinental gene flow, region-specific positive selection, and an ...
Mutational Fingerprints Reveal the Hidden Forces Driving Prostate Cancer
A new Nature study integrates multiple classes of genomic mutations to define the distinct mutational processes that shape prostate cancer ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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