Observational genome study links eight processes to most prostate cancer DNA damage
An observational analysis of 959 prostate tumours from 1,001 men found that eight cellular processes account for 85% of DNA ...
Tag: DNA repair
DNA lesions and repair-gene expression differ in bipolar disorder and sibling groups
A comparison of 127 participants found elevated oxidative DNA lesions and differing nucleotide-excision-repair gene expression in people with bipolar disorder ...
Alzheimer’s tetraploid neurons show enriched somatic single nucleotide variants
A six-brain sequencing study found that Alzheimer’s-associated tetraploid neurons carried excess low-frequency somatic single nucleotide variants, with enrichment for T>C ...
Lab assays find Ganges water extracts show mutagenic and genotoxic effects
Laboratory assays detected mutagenicity, DNA damage and impaired plant growth in Ganges River water extracts containing pharmaceuticals, antibiotics and other ...
Mini-review links chaperone overproduction with oxidative-stress resistance and DNA-repair regulation
A mini-review reports that chaperone overproduction is associated with oxidative-stress resistance and may support DNA repair through interactions with repair-system ...
Genome-wide analysis links tumor deletion patterns to alternative DNA repair
A whole-genome analysis of 2,157 tumors across 17 cancer types identified distinct deletion patterns associated with two backup DNA-repair pathways, ...
Lactylation links glioblastoma metabolism to progression and resistance
A 2026 review links lactate-driven protein lactylation to glioblastoma growth, stemness, immune escape and treatment resistance in preclinical models, while ...
Cell studies link TONSL recognition of histone H3.1 to DNA repair
A University of Ottawa-led cell study found that TONSL recognizes chemical modifications on histone H3.1 to coordinate DNA repair and ...
Free-Base Editing Delivers Cleaner DNA Changes in Crops
A modular cytidine base editor that separates its Cas9 nickase and deaminase produced fewer unwanted DNA changes in moss and ...
Salmonella Response Regulator NarL Found to Control Key DNA Repair Gene
New research shows that the NarL protein binds directly to the promoter of the DNA repair gene ogt in Salmonella ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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