Aspirin May Slow the Aging Clocks of Colon Cells, Study Suggests
A ten-year analysis of healthy colon tissue shows that long-term aspirin users exhibit significant deceleration of epigenetic mitotic clocks in ...
Tag: DNA Methylation
Gene Activity Comes in Bursts: Epigenetics Reshapes the Picture of Transcriptional Noise
A new review argues that transcription occurs in multi-scale bursts shaped by DNA methylation, histone variants, modifications and enhancer looping, ...
Ancient Viral Fossils Awaken in DNMT3A-Mutant Blood Clones, Fueling Inflammation
New research shows that expanded DNMT3A-mutant blood clones awaken dormant retrotransposable elements and drive interferon and NF-kappaB inflammation, while TET2-mutant ...
Epigenetic Clocks Pass a Real-World Test in Rural West Africa
A study of 393 adults in south-central Côte d'Ivoire shows that DNA methylation epigenetic clocks are valid biomarkers of aging ...
Blood Test Clues: Six DNA Methylation Markers Flag the Most Common Kidney Cancer
Japanese researchers have identified six hypomethylated CpG sites in blood DNA that distinguish clear cell renal cell carcinoma patients from ...
Epigenetic clocks reveal how the aging uterus ticks during pregnancy
A first-of-its-kind study shows that epigenetic aging clocks measured in maternal blood can serve as a proxy for the biological ...
Aging and Rejuvenation Converge on the Same Epigenetic Switch in Mouse Skin
Whole-genome sequencing of mouse skin shows that aging and partial reprogramming converge on PRC2 target genes, where methylation entropy rises ...
Smoking May Shorten Colorectal Cancer Survival Most in Tumors With Low LINE-1 Methylation
A prospective cohort study of 1,208 colorectal cancer patients finds that current smoking is linked to substantially worse survival only ...
Dogs’ Epigenetic Clocks Revealed: DNA Methylation Study Maps How Aging Reshapes the Canine Genome
A new GeroScience study of beagles reveals that canine aging proceeds through distinct, stage-specific epigenetic phases in which DNA methylation ...
Blood Cell DNA Fingerprints Could Expose Hidden Inflammation in Diseased Tissue
Researchers have identified DNA methylation markers unique to white blood cells that can quantify immune infiltration in saliva, inflammatory disease ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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