Female X chromosomes show lower methylation than male X in human brain
A chromosome-wide analysis of 89 human brain methylomes finds that the combined methylation of female X chromosomes is globally lower ...
Tag: DNA Methylation
Long-read sequencing maps the hidden 5hmC landscape of human neurons
Using native long-read nanopore sequencing, researchers have simultaneously mapped 5mC and 5hmC across the whole genome of human neuronal nuclei, ...
DNA Methylation of Two Long Non-Coding RNA Loci Tracks Metastatic Disease in Kidney Cancer
DNA methylation at the LINC01354 and LINC01510 long non-coding RNA loci rises with tumor stage, grade and metastatic spread in ...
Urine may reveal aging-related DNA demethylation changes better than leukocytes
A study of healthy volunteers aged 1.5 to 71 found that urinary levels of active DNA demethylation products decline with ...
Blood lipid–linked DNA methylation patterns replicate in Korean adults and tie to epigenetic aging
An epigenome-wide study of 1,527 Korean adults confirms core lipid–methylation loci and links ABCG1 methylation to the association between accelerated ...
Human osteoclast formation drives widespread DNA methylation remodelling, study finds
A genome-wide study of human cells finds 9,006 differentially methylated CpG sites and 1,526 differentially methylated regions during osteoclast differentiation.
Gingival fibroblast-derived iPSCs show broad methylation convergence with residual somatic patterns
A methylation comparison of human gingival fibroblasts, their derived iPSCs and an embryonic stem-cell reference found broad pluripotent-state convergence alongside ...
Molecular Markers May Predict Pituitary Tumor Invasion
A new review in Frontiers in Endocrinology synthesizes molecular biomarkers, including DNA methylation and liquid biopsy indicators, that may help ...
Urinary DNA methylation marker TAGMe offers preoperative risk stratification in urothelial carcinoma
A urine-based DNA methylation marker, TAGMe, was associated with poorer outcomes in urothelial carcinoma and improved preoperative risk prediction in ...
THOR hypermethylation drives hTERT reactivation in cervical cancer
A study of Indian cervical cancer patients links THOR hypermethylation to hTERT reactivation and reduced menin recruitment, independent of HPV ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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