Hidden Chemical Tags on DNA Reveal Immune Chaos in Fragile X-Linked Brain Disease
The first genome-wide methylation map of the FXTAS brain reveals epigenetic changes in immune, oxidative stress, and myelination genes that ...
Tag: DNA Methylation
Staphylococcus aureus SauUSI Motor Revealed as a One-Enzyme DNA Shredder
Single-molecule experiments reveal that one SauUSI restriction enzyme dimer from Staphylococcus aureus acts as an ATP-driven motor that loops along ...
How Maize Remembers Drought: Epigenetic Memory and Seed Priming Could Shield the World’s Vital Cereal Crop
A new review reveals how maize stores molecular memories of past droughts through histone marks, DNA methylation and transposable elements, ...
Genetic Deletion Rewrites the Rules of Methylation Inheritance in Plants
The discovery that VIM2 and VIM4 act as dosage-sensitive negative regulators of CG methylation maintenance forces a reconsideration of how ...
Inherited genome rearrangements shape tumor mutation burden in breast and gynecologic cancers
Inherited changes in the architecture of the human genome, far larger than the single-letter mutations that have dominated cancer genetics ...
DNA Methylation Study Fails to Replicate Epigenetic Scars of Childhood Maltreatment
A preregistered replication study in Translational Psychiatry found that reported DNA methylation signatures of childhood maltreatment subtypes largely failed to ...
Social Media Overuse Linked to Stress-Gene Methylation in First Longitudinal Epigenetic Study
A longitudinal study of depressed patients and healthy controls finds preliminary links between problematic social media use and DNA methylation ...
Chemokine Gene Methylation Tied to Liver Inflammation in Chronic Hepatitis B
Researchers found that reduced methylation of the CXCL16 gene promoter in chronic hepatitis B patients tracks with elevated chemokine expression ...
Stomach Microbes and Genes Team Up to Skyrocket Gastric Cancer Risk
A Japanese study of 620 subjects shows that combining a high-risk gastric microbiome signature with PSCA and MUC1 genetic variants ...
The Methylation Test That Decides Brain Cancer Treatment Faces a Reckoning
A new Mayo Clinic review in the Journal of Neuro-Oncology examines how MGMT promoter methylation guides brain tumor treatment, why ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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