Two-Drug Strike Cripples DNA Repair in Malaria Parasite
New research shows that inhibiting the chaperone PfHsp90 with 17-AAG destabilizes the malaria parasite's Bloom helicase PfBlm and potentiates the ...
Tag: DNA double-strand break repair
DNA Repair Enzyme Pol ι Emerges as Key Player in Early Breast Cancer Risk in BRCA2 Carriers
A new iScience study shows that the error-prone polymerase Pol ι is induced in BRCA2-deficient mammary epithelial cells, where it ...
Loss of Checkpoint Kinase 2 Reshapes How Cells Repair Broken DNA
A new Cell Death & Discovery study shows that checkpoint kinase 2 deficiency alters how cells engage homologous recombination and ...
Archaeal NurA Nuclease Structure Reveals Catalysis and Cooperation in DNA Break Repair
DNA double-strand breaks are among the most dangerous forms of genetic damage a cell can experience. When both strands of ...
Scientists engineer next-generation cancer treatments by disabling tumor DNA repair
DETROIT — Traditional cancer therapies such as radiation and chemotherapy attack tumor cells by damaging their DNA, but many cancers ...
DNA-PK Phosphorylates CRTC2, Boosting NHEJ and Evading Immunity
In a groundbreaking study set to redefine our understanding of DNA repair and its intersection with cancer immunity, researchers have ...
Cancer-Linked Protein Plays Key Role in Tumor DNA Repair
A groundbreaking study from Oregon Health & Science University (OHSU) unveils a previously unrecognized role of the notorious cancer-driving protein ...
Mytho/Phaf1 Shields Danio rerio from DNA Damage
In a groundbreaking study that promises to reshape our understanding of genomic stability and tissue integrity, researchers have unveiled a ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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