Tag: CTCF

A neural ordinary differential equation model learned joint RNA and chromatin dynamics in mouse germinal-center B cells, predicted mutation effects ...

A mouse immune-cell study links inflammation-induced chimeric RNA formation to a functional fusion protein that sharpens the trade-off between bacterial ...

A new opinion article explains how phase separation, loop extrusion, and nuclear membrane adsorption together shape the 3D folding of ...

A massive Hi-C study across eight mouse strains shows that the strength of chromatin boundary insulation predicts how faithfully topologically ...

A new computational framework called DeCTCF uses AI-predicted epigenomic features to sort more than 236,000 CTCF binding sites into 20 ...

An Oxford-developed single-allele chromatin mapping platform called MCCv identifies causal noncoding variants in autoimmune disease and reveals that a neo-CTCF ...

Researchers have discovered that DNA methylation evicts the architectural protein CTCF from the HOXD locus, collapsing a chromatin loop that ...

A new study identifies the frataxin gene FXN as a diagnostic biomarker for primary open-angle glaucoma and shows that the ...

Scientists have shown that removing hidden repressive elements from RNA messages with splice-switching antisense oligonucleotides can boost protein production from ...

Low-dose inhibition of the motor protein KIF11 rebuilds enhancer–promoter loops at the androgen receptor locus, restoring drug sensitivity in otherwise ...