Review maps CRISPR-Cas9 advances in editing precision, delivery and therapeutic applications
A 2026 review summarizes advances in CRISPR-Cas9 precision, delivery and primary-cell engineering for genetic diseases and diabetes, while the available ...
Tag: CRISPR-Cas9
FsMP co-transformation achieves 95% leaf transformation in optimized Forsythia hairy-root protocol
An experimental protocol study achieved 95% leaf transformation efficiency in Forsythia suspensa through FsMP co-transformation in an optimized hairy-root system.
Donald Kohn’s Gene Therapy Breakthroughs Earn Medical Academy Honor
UCLA physician-scientist Donald Kohn’s election to the National Academy of Medicine honors decades of work advancing blood stem cell gene ...
CRISPR Editing Route, Not Just Target Genes, Reshapes CHO Cell Lines
A systematic comparison shows that sequential and multiplex CRISPR/Cas9 workflows produce CHO cell lines with the same nine hydrolase knockouts ...
Ancient Hox9–10 genes reveal the hidden origins of vertebrate hind fins and limbs
Hox9–10 genes act at the earliest stages of pelvic fin and hindlimb development in zebrafish and newts, revealing a conserved ...
Single Gene Knockout Strips Lab-Grown Heart Cells of Immune Visibility
Researchers used CRISPR-Cas9 to knock out the TAPBP gene in human induced pluripotent stem cells, producing cardiomyocytes with sharply reduced ...
Nanoparticles may carry CRISPR gene editing into infant neuroblastoma
Infant neuroblastoma is one of the most clinically paradoxical cancers in medicine. Diagnosed during the first year of life, it ...
Zebrafish With Truncated Plakophilin-2 Reveal How a Common Heart Gene Mutation Triggers Deadly Arrhythmias
Researchers have generated the first stable zebrafish model of PKP2-linked arrhythmogenic cardiomyopathy, revealing fat infiltration, conduction defects, and exercise-induced sudden ...
Anionic Additive Helps Peptide Carriers Release siRNA and CRISPR Cargo Inside Cells
A study of arginine/tryptophan peptides shows that strong carrier-cargo binding blocks gene silencing, and adding a negatively charged component restores ...
Pig Hearts for People: The Science and Ethics Behind the First Clinical Xenotransplant Trials
A new perspective argues that the first FDA-cleared clinical trial of gene-edited pig hearts marks a turning point, but that ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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