Tag: clonal hematopoiesis

A large Mendelian randomization study links genetically predicted clonal hematopoiesis of indeterminate potential to increased risks of six cancer types, ...

An autopsy-confirmed case reveals shared STAT3 and TET2 mutations linking Felty syndrome to terminal aggressive clonal T-cell disease.

New research shows carboplatin drives the expansion of TP53-mutant blood clones far more strongly than PARP inhibitors, while inherited homologous ...

A new conditional knockout mouse model shows that loss of the epigenetic regulator Tet2, combined with aging and a reshaped ...

A new framework in the Journal of Translational Medicine defines when blood-cell clones should be treated as sequencing artifacts, host ...

A retrospective study of 354 patients found clonal T-large granular lymphocyte expansions in 17.2 percent of JAK2-mutated myeloproliferative neoplasm cases, ...

Single-cell and spatial analyses of human bone marrow reveal that clonal hematopoiesis of indeterminate potential is marked by fibroblast expansion, ...

A new review argues that somatic mosaicism is a pervasive feature of the human brain that links development, ageing and ...

Single-cell multiomics of blood stem cells from myeloproliferative neoplasm patients shows that interferon-α normalizes blood counts by boosting lymphoid differentiation ...

A new study published in Nature Communications reports a longitudinal map of mosaic chromosomal alterations, tracking how these genomic events ...