Engineered Herpes Viruses Show Modest but Meaningful Gains Against Solid Tumors
A meta-analysis of 38 clinical trials finds oncolytic herpes simplex virus therapy delivers modest anti-tumor activity across solid tumors, with ...
Tag: Clinical Trials
Muscle MRI Fat Fraction Emerges as a Powerful Biomarker of Mitochondrial Myopathy Severity
A prospective study of 49 adults shows that quantitative MRI fat fraction objectively measures disease severity in mitochondrial myopathies, correlating ...
New Four-Axis Framework Maps the Hidden Diversity of Atypical Alzheimer’s Disease
A new review proposes a four-axis framework of clinical phenotype, biological context, network topography, and tempo to define the heterogeneity ...
Four Asia-Pacific Nations, Four Paths: Why Cancer Genomics Success Hinges on Health Systems, Not Sequencers
A landmark comparative review finds that Japan, South Korea, China, and Australia have all mastered the technology of cancer genomics, ...
Invasive Lobular Carcinoma Research Takes Center Stage at 7th International Symposium
Selected abstracts from the seventh biannual International Invasive Lobular Carcinoma Symposium, published in Breast Cancer Research and Treatment, showcase the ...
Scientists Clash Over Free Water Imaging as a Marker of Parkinson’s Disease Progression
A published exchange in npj Parkinson's Disease highlights the methodological debate over whether free water imaging can reliably serve as ...
Therapeutic Vaccines for Ovarian Cancer Show Promise but Remain Stuck in Early-Stage Trials
A comprehensive analysis of 136 registered clinical trials reveals that therapeutic vaccines for ovarian cancer have advanced steadily for three ...
Sarcoma Trials Offer Blueprint for Rarer Cancers Under New WHO and Global Trial Rules
A new review in eClinicalMedicine shows how sarcoma trials can guide the implementation of the 2024 WHO guidance and ICH ...
Hormone Receptor Testing Rarely Guided Endocrine Therapy for Breast DCIS in New Zealand
A 23-year New Zealand population study found that oestrogen receptor testing and endocrine therapy for DCIS remained rare nationally, driven ...
Commentary Challenges Claims of Exceptional Melflufen Responses in Multiple Myeloma
A new commentary argues that exceptional long-term responses to melflufen-dexamethasone in myeloma case reports should not override subgroup trial evidence ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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