Clinical Trials

A new therapy developed by researchers at Rush University Medical Center is showing success as a way to prevent COVID-19 symptoms in mice. In a study published in the Journal of Neuroimmune Pharmacology, mouse models with COVID-19…

Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, January 19, 2021--Gene editing therapies, including CRISPR-Cas systems, offer the potential to correct mutations causing inherited retinal degenerations, a leading cause of…

The team led by Bruno Silva Santos, Principal Investigator and Deputy Director of the Instituto de Medicina Molecular João Lobo Antunes (iMM) and Professor at the Faculdade de Medicina da Universidade de Lisboa, discovered that the…

MS research team led by John DeLuca, PhD, will conduct study to assess effects of Tysabri on cognitive fatigue, a common symptom that can cause disability among individuals with multiple sclerosisCredit: Kessler Foundation East…

New non-steroidal topical drug benvitimod proven to be safe and effective for plaque psoriasis in a phase III clinical trial in ChinaCredit: Pexels Psoriasis is a chronic inflammatory skin disease characterized by erythematous (red)…

Summary Ultra-small nanomedicines of approximately 18 nm were fabricated by dynamic ion-pairing between Y-shaped block copolymers and nucleic acid drugs, such as siRNA and antisense drugs. Chemically modified and double-stranded…

Researchers developed an artificial intelligence system for analyzing endoscopic imagesCredit: Peter the Great St.Petersburg Polytechnic University Researchers of Peter the Great St.Petersburg Polytechnic University (SPbPU), in…

Credit: ISGlobal/Clínica Universidad de Navarra. A small pilot study suggests that early administration of ivermectin can reduce viral loads and symptom duration in patients with mild COVID-19, which in turn could help reduce viral…

Credit: Gut 2021 BEER-SHEVA, Israel...January 18, 2021 - A green Mediterranean (MED) diet reduces intrahepatic fat more than other healthy diets and cuts non-alcoholic fatty liver disease (NAFLD) in half, according to a long-term…

Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, January 15, 2021--The biodistribution of adeno-associated virus (AAV) gene transfer vectors can be measured in nonhuman primates using a new method. The method quantifies…

She led team that discovered first COVID-19 case of community spread in the United States SEATTLE (January 15, 2021) - A University of Washington physician and professor, whose team of researchers identified the first case of the…

Credit: Virginia Tech The Clinical and Translational Science Award (CTSA) hub partnership between Virginia Tech, the University of Virginia, Carilion Clinic, and Inova Health System has awarded $200,000 in funding to five research…

Phase 2 clinical trial involving CHOP and the Neurofibromatosis Clinical Trials Consortium showed cabozantinib reduced tumor volume and pain Philadelphia, January 14, 2021--Based on preclinical studies of an investigational drug to treat…

BrainQ Technologies awards funding to Drs. Androwis and Kirshblum for pilot study of BQ therapy at Kessler Foundation for restoring arm and hand function in individuals with traumatic spinal cord injuryCredit: BrainQ Technologies …

HOUSTON - (Jan. 14, 2021) - Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and…

Rush leads new CDC-funded study, launches post-COVID clinicCredit: INSPIRE for COVID-19 COVID-19 has wreaked havoc around the globe, causing nearly 2 million deaths worldwide, including more than 380,000 fatalities in the United…

Credit: KIRSTY CHALLEN, B.SC., MBCHB, MRES, PH.D., LANCASHIRE TEACHING HOSPITALS, UNITED KINGDOM. DES PLAINES, IL -- Among children who were not in an independently verified incident, evaluation for child abuse should be done by…

University of Houston researcher tackles proteins found in diseaseCredit: University of Houston Among the primary forms of kidney disease, focal segmental glomerulosclerosis (FSGS) is the most common and is marked by high circulating…

Cardiologists perform catheter-based repair of leaky tricuspid heart valve HOUSTON-(Jan. 13, 2020)- Cardiologists Dr Sachin Goel and Dr Stephen Little at Houston Methodist recently performed the first catheter-based repair in Houston of a…

Established in 2019 in Nashville, COMBINEDBrain is a non-profit consortium of patient advocacy groups, researchers and clinicians working together to fast-track cures and therapies for individuals afflicted with rare genetic…