RAS Inhibitor Daraxonrasib Redefines Pancreatic Cancer Treatment After FDA Approval
A phase 3 trial of the pan-RAS inhibitor daraxonrasib doubled median overall survival in previously treated metastatic pancreatic cancer, prompting ...
Tag: Clinical Trials
AI-guided coronary CT angiography may sharpen cardiovascular risk assessment in diabetes
A new perspective article argues that coronary CT angiography, enhanced by artificial intelligence, could help clinicians stratify cardiovascular risk in ...
Fluted Pumpkin Review Finds Rich Nutrients but Mostly Preclinical Health Evidence
A new review finds fluted pumpkin is rich in protein, minerals and bioactive phytochemicals, but nearly all of its reported ...
Checkpoint Inhibitors Show Promise for People With HIV, but Africa Remains Excluded
A new review finds checkpoint inhibitors are safe and effective for virologically suppressed people with HIV, while sub-Saharan Africa remains ...
Herbal medicines face a hard road from tradition to clinical proof
A narrative review maps why complex herbal formulations struggle to meet modern clinical and regulatory standards worldwide.
Baseline Amyloid Levels Predict One-Year Clearance on Donanemab, Analysis Shows
A post hoc analysis of the TRAILBLAZER-ALZ 2 trial found that lower baseline amyloid, older age, fewer APOE ε4 alleles ...
Engineered Cancer-Killing Viruses Move From Lab Curiosity to Approved Therapy
A new review details how engineered oncolytic viruses selectively kill tumors, ignite antitumor immunity, and where clinical translation still falls ...
Berberine shows promise against type 2 diabetes, but clinical proof is still lacking
A new narrative review finds berberine may influence multiple pathways in type 2 diabetes, but most evidence remains preclinical and ...
Locoregional therapies plus immunotherapy reshape care for unresectable liver cancer
A new review finds that combining immune-checkpoint inhibitors with locoregional therapies improves progression-free survival in hepatocellular carcinoma, but overall survival ...
New Estimator Targets Hypothetical Trial Effects When Time-to-Event Events Intervene
Researchers have developed a generalized Nelson–Aalen estimator that targets hypothetical estimands via the controlled direct effect when time-to-event intercurrent events ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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