Clinical Trials

National registry and trial will evaluate hydroxycholoroquine as preventive drug for coronavirus DURHAM, N.C. -- The Patient-Centered Outcomes Research Institute has funded up to $50 million to evaluate hydroxychloroquine (HCQ) as a…

Duke Clinical Research Institute to build registry of healthcare workers and conduct trial of infection prevention in healthcare workers using PCORnet® WASHINGTON (April 1, 2020) - The Patient-Centered Outcomes Research Institute (PCORI)…

Duke Clinical Research Institute to build a healthcare worker community registry and conduct a randomized trial powered by PCORnet®, the PCORI-funded health research network WASHINGTON (April 1, 2020) - The Patient-Centered Outcomes…

14,000 Nevadans quickly report on signs and symptoms to enhance predictive public health models for NevadaCredit: DRI Reno, Nev. (March 31, 2020) - The Healthy Nevada Project, a first-of-its-kind, community-based population health…

Investments in LGG research to transform patient care: Congratulations to Gilbert Family Foundation for sponsoring first-rate consensus workshop and gratitude to Synodos LGG donorsCredit: CTF A paper published in the…

Since the onset of the COVID-19 crisis the subject of personal protective equipment (PPE) has become a key discussion point. Over recent days the focus has been on the supply of facemasks that allow healthcare workers to interact safely…

Credit: Phil Jones, Augusta University Senior Photographer AUGUSTA, Ga. (April 1, 2020) - A low-cost, noninvasive treatment that uses the power of the magnet to stimulate and heal nerves key to bowel control is under study for the…

Developed by researchers at the Butantan Institute (Brazil) and Boston Children's Hospital, part of the Harvard Medical School (USA), the innovation is capable of providing protection against all serotypes of the bacterium Streptococcus…

Three previously unknown genetic mechanisms have been discovered in causing myopia otherwise known as short or near-sightedness, finds a new study. The study, published today in Nature Genetics, led by King's College London, UCL and…

Stellenbosch University (SU) in South Africa and AzarGen Biotechnologies (Pty) Ltd, a South African biotechnology company, have joined forces in the global fight against the coronavirus Stellenbosch University (SU) in South Africa and…

What we learned from the first known community-acquired coronavirus case in the US (SACRAMENTO, Calif.) - When UC Davis announced the first case of community transmission of COVID-19 in the U.S. on Feb. 26, it solved a medical mystery at…

Credit: Sarah Pack, Medical University of South Carolina The South Carolina Clinical & Translational Research (SCTR) Institute, one of about 60 Clinical and Translational Award (CTSA) hubs nationwide, has been awarded a…

Test proved able to detect and indicate site of dozens of types of cancer with high accuracy according to recent study; Dana-Farber joins multi-center trial to provide test results to patients for the first timeCredit: Editorial Figure by…

Symptoms and test findings show tendency to ebb and flow, but still raise risk Patients who experience chest pain and have abnormal results on a cardiac stress test but who do not have blocked arteries often experience changes in their…

PCSK9 inhibitor evaluated for treating homozygous familial hypercholesterolemia The cholesterol drug alirocumab reduced low-density lipoprotein (LDL) cholesterol by 35.6% compared to placebo in adult patients with homozygous familial…

Credit: Houston Methodist HOUSTON-(March 28, 2020) - Houston Methodist received FDA approval Saturday to become the first academic medical center in the nation to transfuse donated plasma from a recovered COVID-19 patient into a…

Monoclonal antibody effective for the full spectrum of homozygous familial hypercholesterolemia The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol to near-normal levels among patients with a rare…

As with lowering LDL, raising EPA with icosapent ethyl helped lower CVD risk, study finds Higher levels of the omega-3 fatty acid eicosapentaenoic acid (EPA) found in the blood--and not a decrease in triglyceride levels as originally…

People receiving a stent are more likely to need a repeat procedure to open the blocked artery In a study with the longest follow-up to date of patients with a high-risk form of heart disease known as left main coronary artery disease…

Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, March 30, 2020--A new study quantifies the future economic burden of cardiovascular disease (CVD) in women with a history of preterm delivery (PTD). The study, which used a…