Platform Trials Promise Faster Answers but Face Serious Methodological Pitfalls
A new review finds adaptive platform trials offer real efficiency gains but are often undermined by weak blinding, non-concurrent controls ...
Tag: clinical trial design
Implementation Science Principles Shape Scalable Early Therapy for Infants at Risk of Motor Delay
Researchers embedded implementation science principles into an ongoing infant physical therapy trial to make early neuromotor interventions ready for rapid ...
Faster Brain Stimulation for Depression Needs Dose, Spacing and Durability Proof, Not Just Speed
A new opinion article argues that accelerated transcranial magnetic stimulation for depression should be evaluated as a constrained optimization of ...
Blood Pressure Cuff Technique Shows Early Safety Promise for Severe Childhood Brain Condition
A commentary in Pediatric Research finds that remote ischemic postconditioning is safe and feasible in children with AESD, clearing the ...
Zero Events, False Comfort: Why Less Oxygen Before Extubation Is Not Yet Proven Safer
A new correspondence in Pediatric Research argues that a trial showing less lung collapse with 50 percent pre-extubation oxygen in ...
Old Drugs, New Tricks: How Repurposing Could Crack Cancer’s Resistance Problem
A new review in Molecular Cancer maps how approved drugs from outside oncology could be repurposed, under a strict mechanism-first ...
Remote Pain Care Dyad Aims to Close the Cancer Pain Gap for Rural and Hispanic Patients
A new randomized clinical trial protocol tests whether a remote, collaborative care model pairing pain specialists with community health workers ...
Why Head and Neck Cancer Rehab Trials Must Stratify for Lymphoedema
A new correspondence in Supportive Care in Cancer argues that head and neck cancer rehabilitation trials must stratify participants by ...
Human Milk Diets and Preterm Growth: What the JASMINE Trial Really Tested in Japanese NICUs
A new editorial defends the JASMINE trial's finding that exclusive human milk-based diets improved growth in Japanese very low birth ...
Scientists Redesign Eating Disorder Trials by Sharing Power with Patients
Researchers in Australia have published a detailed blueprint for co-producing eating disorder treatment trials, in which people with lived experience ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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