New Benchmark REACH Exposes How Rare Cancer Cell Detection Methods Collapse Under Pressure
A new reproducible benchmark called REACH evaluates ten computational methods for detecting rare malignant cells in single-cell RNA sequencing data, ...
Tag: circulating tumor cells
Computational Study Links Metabolic Enzyme NNMT to a Triple Shield That Lets Cancer Cell Clusters Survive in the Bloodstream
A new computational framework links the metabolic enzyme NNMT to coordinated platelet, neutrophil, and immune exhaustion programs in circulating tumor ...
Liquid Biopsy Catches Cancer Cells Slipping Into Blood During Cervical Cancer Surgery
A preliminary French feasibility study detected circulating tumor cells in the blood of patients during laparoscopic surgery for early-stage cervical ...
Circulating Tumor Cells and Tumor Size Combine to Guide Liver Cancer Surgery Margins
A multicenter retrospective study of 383 patients shows that preoperative circulating tumor cell status combined with tumor diameter can guide ...
Hidden Switch Lets Melanoma Cells Flip Into Metastasis Mode, Study Finds
Researchers in Milan have identified MyD88 as a tumor cell-intrinsic switch that sustains a metastasis-competent, integrin-driven cell state in NRAS-mutant ...
Sound-Powered Microchip Sorts Tumor Cells From Nanoscale Debris With Near-Perfect Recovery
A 3.75 MHz surface-acoustic-wave microchip achieved up to 99.4 percent recovery of MCF-7 tumor-cell models while routing cellulose-nanofiber suspensions to ...
Liposomal Quercetin Blocks Lung Cancer Spread in Mice, With Liquid Biopsies Tracking Every Step
Liposome-encapsulated quercetin completely suppressed liver metastasis in a mouse model of lung cancer while liquid biopsy cell analysis and ex ...
AI Learns to Design Tiny Chips That Fish Cancer Cells Out of Blood
Researchers used Bayesian optimization with Gaussian process surrogate modeling to design microfluidic deterministic lateral displacement chips that separate circulating tumor ...
Scientists Engineer Shear-Resistant Prostate Cancer Cells and Uncover a Survival Gene
Researchers have created the first stable prostate cancer cell lines resistant to blood-flow-level shear stress and identified the calcium-buffering gene ...
Microfluidic Chip and Deep Learning Join Forces to Catch Rare Tumor Cells in Blood
Researchers at Taiyuan University of Technology and Shanxi Bethune Hospital have developed a label-free platform that combines inertial microfluidic cell ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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