Silencing NOTCH1 Makes Leukemia Cells Vulnerable to CD19 CAR-T Attack
New research shows that blocking the NOTCH1 signaling pathway prevents leukemia cells from degrading the CD19 antigen, making them far ...
Tag: chronic lymphocytic leukemia
Leukemia’s Shifting Map: Asia’s Three-Decade Cancer Burden Reimagined
A sweeping 30-year analysis of Global Burden of Disease data across 49 Asian countries reveals that leukemia incidence has surged ...
Real-World Data Show Zanubrutinib Delivers Strong Results in 410 Leukemia Patients
A nationwide cohort of 410 patients shows zanubrutinib delivers high progression-free survival in CLL/SLL, with dose reductions and switches between ...
New AI Tool MANTRA Reads Leukemia Data in Multiple Dimensions to Reveal Hidden Patient Subgroups
A new Bayesian framework called MANTRA jointly analyzes three-dimensional drug-response data and two-dimensional gene expression matrices, revealing clinically relevant leukemia ...
Brain Shape May Help Explain Why Blood Cancer Rates Differ Between Ancestries
A Mendelian randomization study finds that inherited differences in cerebral cortical structure are causally linked to blood cancer risk and ...
Ibrutinib Triggers Matriptase to Preserve CD19 and Block Antigen Escape in B-Cell Malignancy
New research shows that the BTK inhibitor ibrutinib activates the protease matriptase in malignant B cells, preserving surface CD19 and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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