ACSS2 inhibition boosts cabozantinib activity in liver cancer models
Preclinical hepatocellular carcinoma models showed that blocking ACSS2 or autophagy enhanced cabozantinib’s antitumor activity by disrupting a TFEB-linked protective response.
Tag: chloroquine
Cellular Recycling Machine Linked to Male Fertility Hormone Control
New research reveals that the cellular recycling protein p97/VCP directly regulates the autophagic degradation of androgen-binding protein in Sertoli cells, ...
Calcium-Rich Bone Environment Helps Osteosarcoma Cells Survive Chemotherapy
Researchers have discovered that the calcium-rich bone microenvironment drives chemotherapy tolerance in osteosarcoma through an ORAI3–Ca²⁺–NFAT4–PINK1 mitophagy axis that can ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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