PIK3CA silencing restores anoikis sensitivity in endothelial cells
In vitro PIK3CA silencing restored anoikis sensitivity and reduced aggressive behaviors in engineered anoikis-resistant rabbit aortic endothelial cells.
Tag: cell invasion
GFPT1 silencing curbs aggressive esophageal cancer cell behavior through ER stress
Cell experiments found that silencing GFPT1 reduced proliferation, migration and invasion in esophageal cancer cells, with a rescue experiment supporting ...
SERPINB5 promotes pancreatic adenocarcinoma progression through FBXO32-mediated regulation of epithelial-mesenchymal transition
Transcriptomic and pancreatic adenocarcinoma cell-model analyses linked SERPINB5 to malignant cell phenotypes through FBXO32-associated regulation of epithelial–mesenchymal transition.
Cell study finds IL-1β amplifies TGF-β1 effects in SK-Hep1 cells through p38 MAPK-linked SMAD2/3 signaling
An in vitro SK-Hep1 cell study found that IL-1β enhanced TGF-β1-induced fibronectin and N-cadherin expression, migration and invasion through a ...
Itaconate-treated macrophage exosomes boost breast cancer cell invasion in vitro
In vitro experiments found that exosomes from dimethyl-itaconate-treated macrophages increased EMT-associated changes, migration, and invasion in MCF-7 breast cancer cells ...
IL1RAP associated with aggressive features in papillary thyroid carcinoma
IL1RAP was associated with aggressive features in papillary thyroid carcinoma, while cell experiments linked its expression to proliferation, invasion, EMT-like ...
Stem Cell Gene Sox2 Study in Bone Cancer Retracted Over Manipulated Images
The journal Pathology & Oncology Research has retracted a 2018 osteosarcoma study after the authors reported improper image cropping, with ...
Fgl-1 Emerges as an Oncogenic Driver Fueling Endometrial Cancer Through PI3K/AKT Signaling
New research shows that fibrinogen-like protein 1 is overexpressed in endometrial adenocarcinoma and drives tumor growth, migration and invasion by ...
Neurexophilin 4 Emerges as a Molecular Driver of Kidney Cancer Through PI3K/AKT-Controlled Glycolysis
New research reveals that the protein neurexophilin 4 drives the growth, invasion and metabolic reprogramming of clear cell renal cell ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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