Tag: cell invasion

A study shows that the enzyme MGAT3 curtails lung adenocarcinoma malignancy and dampens EGFR/AKT/ERK signaling in cell-line models.

A study reveals that high miR-2278 expression independently predicts shorter relapse-free survival and drives lung squamous cell carcinoma progression partly ...

An integrated transcriptomic and experimental analysis revealed that elevated malignant cell abundance and MT2A expression correlate with poor prognosis in ...

A study in Discover Oncology finds that silencing TPX2 suppresses glycolysis and malignant traits in colorectal cancer cells, with PKM2 ...

Researchers developed a machine-learning pathomics model using patient data from TCGA to predict NRG1 expression in bladder cancer.

Preclinical study findings indicate that long non-coding RNA TRHDE-AS1 suppresses melanoma cell growth by upregulating SPRED1 and dampening MAPK/ERK pathway ...

A study demonstrates that the PIKfyve inhibitor APY0201 suppresses esophageal cancer cell invasion and stemness while inducing ferroptosis through the ...

Researchers identified an epigenetic mechanism in which histone H3K9 lactylation accelerates hepatocellular carcinoma progression by activating LUC7L2 to destabilize SPINK13 ...

Researchers found that elevated deoxycholic acid promotes colorectal cancer progression by polarizing macrophages toward an immunosuppressive phenotype that triggers tumor ...

Downregulation of the transcription factor RFX2 promotes immune escape and tumor progression in lung adenocarcinoma by suppressing RASSF1 and reducing ...