Cobalt Compound Halts Colorectal Cancer Cells by Jamming CDK4/6 and BCL2
A mononuclear octahedral cobalt(III) Schiff base complex arrests HT-29 colorectal cancer cells at the G1/S and G2/M checkpoints and triggers ...
Tag: CDK6
Old Breast Cancer Drug Ormeloxifene Pushes Tumor Cells Into Irreversible Senescence
A new study shows that the decades-old contraceptive drug ormeloxifene drives breast cancer cells into irreversible senescence and enhances their ...
Space Radiation Leaves Distinct Mutational Fingerprints in Mouse Liver Tumors
Whole genome sequencing of liver tumors in outbred mice reveals distinct mutational fingerprints of heavy-ion and gamma-ray radiation, including frequent ...
AI-Powered Virtual Screening Uncovers Potent New Dual CDK4/6 Cancer Inhibitor
Researchers fused machine learning, molecular docking and molecular dynamics simulations into a virtual screening pipeline that discovered HY-18,623, a nanomolar ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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