Lipid Nanoparticle CAR Engineering Reveals Synergy Between T Cells and Macrophages Against Leukemia
A new study shows that lipid nanoparticle-delivered CAR mRNA engineers both human T cells and macrophages against CD19-positive leukemia cells, ...
Tag: CD47
The Don’t Eat Me Signal: How CD47 Shapes Cell Clearance in Cancer, Heart Disease and the Brain
A new review details how the CD47 don't eat me signal regulates efferocytosis and shapes disease outcomes in cancer, atherosclerosis ...
Immune ‘Don’t Eat Me’ Protein CD47 Drives Chemotherapy-Induced Heart Aging in Male Mice
New research shows that the immune checkpoint protein CD47 rises in doxorubicin-damaged hearts and that blocking it with an antibody ...
Tiny DNA Insert in a Super-Enhancer Fine-Tunes Two Cancer Genes in Breast Tumors
A common germline insertion within a bifunctional super-enhancer dampens the expression of the cancer-promoting genes LINC00636 and CD47 in breast ...
Red Blood Cell Disguise Edges Out PEG in Head-to-Head Test of Stealth Nanoparticles
A controlled head-to-head study finds that doxorubicin-loaded albumin nanoparticles camouflaged with red blood cell membranes slightly but significantly outperform PEGylated ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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