Simple Blood Ratios Outperform Standard Scores for Spotting Cirrhosis in Suppressed Hepatitis B
A new study finds that the Prognostic Nutritional Index and monocyte-to-lymphocyte ratio outperform FIB-4 and APRI for detecting cirrhosis in ...
Tag: cccDNA
Epigenetic Silencer Therapy Aims to Switch Off Viral DNA in Chronic Hepatitis B
An investigational epigenetic silencer therapy reported in Nature Biomedical Engineering aims to transcriptionally inactivate hepatitis B viral DNA by locking ...
Why Chronic Hepatitis B Still Defies a Functional Cure: New Review Maps the Immunological Barriers
A new review in Virology Journal explains how cccDNA persistence, viral genome integration and multi-level immune exhaustion keep functional cure ...
Hidden hepatitis B: how occult infection evades tests and threatens patients
A new review in Nature Reviews Gastroenterology & Hepatology explains how occult hepatitis B virus infection persists undetected despite negative ...
Folded DNA Structures in the Hepatitis B Genome Steer Viral Gene Expression
New research shows that conserved G-quadruplex structures in the hepatitis B virus genome recruit host proteins HNF4A and CNBP to ...
Epigenetic Editing Offers Safer Route to Functional Hepatitis B Cure
A new review argues that programmable epigenetic editors could functionally cure chronic hepatitis B by durably silencing viral cccDNA and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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