Ibogaine Shows Promise Against Addiction, but Cardiac Risks Loom Large
A new review in Advances in Therapy finds that the psychedelic alkaloid ibogaine shows broad anti-addictive potential across opioid, stimulant, ...
Tag: cardiotoxicity
Immune Cells That Attack the Heart: Multi-Omics Study Reveals Signature of Checkpoint Inhibitor Myocarditis
A multi-omics study identifies ISG15-positive CD8 T cells and a CCL2-CCR2-mediated inflammatory loop as drivers of immune checkpoint inhibitor-induced myocarditis, ...
Shikonin Shields the Heart From Chemotherapy Damage by Restoring Mitochondrial Balance
A new study in rats and cardiac cells shows that the natural naphthoquinone shikonin protects the heart from doxorubicin chemotherapy ...
Exercise May Not Shield the Heart From Breast Cancer Drugs, Review Finds
A new systematic review and meta-analysis of randomized trials finds that current evidence does not confirm a consistent cardioprotective effect ...
Cat Cancer Drug Epirubicin Shows Mostly Mild Side Effects in Landmark Study of 66 Feline Patients
A retrospective study of 66 cats treated with the anthracycline chemotherapy drug epirubicin found that side effects were mostly mild ...
When Steroids Fail: Drug Combo Rescues Cancer Patient From Deadly Immunotherapy Heart Complication
A case report from Zhongshan Hospital describes how early second-line immunosuppression with tofacitinib and mycophenolate mofetil rescued a 77-year-old woman ...
Cancer Immunotherapy Triggered a Heart Attack in One Patient—Here’s What It Reveals
A new case report describes a 70-year-old lung cancer patient with no cardiovascular risk factors who suffered a massive heart ...
Immune ‘Don’t Eat Me’ Protein CD47 Drives Chemotherapy-Induced Heart Aging in Male Mice
New research shows that the immune checkpoint protein CD47 rises in doxorubicin-damaged hearts and that blocking it with an antibody ...
Fibroblast Protein GNL3 Emerges as Hidden Culprit in Chemotherapy Heart Damage
New research in mice shows that the nucleolar protein GNL3, produced by cardiac fibroblasts, worsens doxorubicin-induced heart injury by driving ...
Stem Cell Screening Platform Hunts for Drugs to Halt Cardiac Fibrosis
Stanford researchers have published a protocol for a high-throughput stem cell-based screening platform that identifies potential antifibrotic compounds for cardiac ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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