Tag: cardiomyocytes

A new review argues that the longevity enzyme sirtuin 1 sits at the molecular crossroads between cellular senescence and heart ...

Researchers have developed a systemically administered nanosystem that captures circulating endothelial exosomes and redirects them to ischemic heart tissue, improving ...

Researchers at Sanford Burnham Prebys report that temporarily blocking the metabolic enzyme succinate dehydrogenase triggers an epigenetic switch in mouse ...

A multi-omics study has mapped stage-specific lipid remodeling across human stem cell differentiation into cardiomyocytes, revealing that polyunsaturated phospholipids accumulate ...

New research in PLOS Genetics identifies the ZBED6–MEOX1–ERK1/2 axis as a key regulator of pathological cardiac hypertrophy through impaired autophagy.

A new mouse study shows that heatstroke depletes the anti-inflammatory lipid Maresin1 and that restoring it through the cardiomyocyte receptor ...

A multi-platform transcriptomic atlas of the human right ventricle reveals a two-phase progression to failure, with early erosion of protective ...

A nine-month study in mice shows that chronic senolytic treatment and aerobic exercise each reduce senescent cell markers in the ...

New research shows that salvianolic acid B, a polyphenol from red sage, protects human heart muscle cells from high-glucose injury ...

Injecting healthy mitochondria from stem cells into aged mice restored cardiac function by reactivating a blocked mitochondrial waste-disposal pathway controlled ...