Tag: CAR-T therapy

A new review charts how in vivo CAR-T engineering could transform customized living drugs into scalable, off-the-shelf genetic medicines.

A multi-stakeholder study finds that current patient-reported outcome measures fail to capture the full side-effect burden and emotional strain of ...

Danish researchers report that low-level skipping of CD19 exon 2, detectable in pre-treatment RNA-sequencing data, correlates with relapse after anti-CD19 ...

A new review maps where the off-label anti-CD20 antibody rituximab fits in the treatment of systemic lupus erythematosus, from refractory ...

A new review finds that subcutaneous immunoglobulin replacement offers steadier antibody levels, fewer systemic side effects and home-based convenience compared ...

A Chinese clinical study reports that donor-derived anti-CD19 CAR-T cells achieved complete remissions in 13 of 14 patients whose B-cell ...

A two-round expert elicitation among German and Austrian hematologists has produced a consensus list of prognostic factors and treatment-effect modifiers ...

Hematologists argue that preventive dental care and oral health assessment should become a standard part of the CAR-T cell therapy ...

A systematic review of nine studies finds that therapy-related myeloid neoplasms after CAR-T therapy emerge earlier and carry worse survival ...

A new review in Annals of Hematology details how molecular profiling and a growing arsenal of targeted and immune-based therapies ...