Liquid Droplets Inside Cells Emerge as Promising New Targets for Cancer Therapy
A new review details how dysregulated liquid–liquid phase separation drives cancer and how engineered peptides, modification mimics and synthetic condensates ...
Tag: Cancer Therapy
Engineered Herpes Viruses Show Modest but Meaningful Gains Against Solid Tumors
A meta-analysis of 38 clinical trials finds oncolytic herpes simplex virus therapy delivers modest anti-tumor activity across solid tumors, with ...
Cryo-EM Reveals How the ATR Checkpoint Kinase Flips Its Molecular Switch
New cryo-EM structures of human ATR–ATRIP in multiple functional states reveal how ATP priming, TopBP1 binding and autophosphorylation activate the ...
Aptamer-Guided CRISPR-Cas9 Delivery Could Make Cancer Genome Editing Precise
A new review outlines how aptamer-guided nanocarriers could finally deliver CRISPR-Cas9 gene editing specifically to tumor cells, integrating molecular targeting, ...
Two-Nanometer Silica Shell Supercharges Iron Oxide Nanoparticles for Cancer-Heating Therapy
Scientists found that an ultrathin two-nanometer silica coating significantly outperforms thicker coatings and no coating at all in boosting the ...
Plant Compound p-Coumaric Acid Fights Liver Cancer by Boosting ROS
A new study shows that the natural plant compound p-coumaric acid suppresses liver cancer by disrupting mitochondria, blocking the Nrf2 ...
Nanoparticles Emerge as a Powerful New Weapon Against Cellular Aging
A comprehensive review in Biogerontology argues that engineered nanoparticles could overcome the solubility, stability, and targeting limitations of senolytic drugs, ...
Ocean Microbes Yield Supercharged Enzymes Against Inflammation, Cancer, and Superbugs
A comprehensive review reveals that enzymes from marine microbes, hardened by extreme ocean conditions, show remarkable potential for treating chronic ...
Dual PROTACs Close In on Two Disease Proteins at Once
A new review in Molecular Diversity charts the rapid rise of dual PROTACs, single molecules engineered to destroy two disease-driving ...
NINJ1: The Membrane-Rupturing Protein That Decides How Cells Die and How Tumors Thrive
A new review in the Journal of Cancer Research and Clinical Oncology examines how the NINJ1 protein executes plasma membrane ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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